Gene: MESD
Official Full Name: mesoderm development LRP chaperoneprovided by HGNC
Gene Summary: Predicted to enable low-density lipoprotein particle receptor binding activity. Involved in ossification and protein folding. Located in endoplasmic reticulum. Implicated in osteogenesis imperfecta type 20. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29745 | MESD Knockout cell line (HeLa) | Human | MESD | 1:3~1:6 | Negative | Online Inquiry |
KO29746 | MESD Knockout cell line (HCT 116) | Human | MESD | 1:2~1:4 | Negative | Online Inquiry |
KO29747 | MESD Knockout cell line (HEK293) | Human | MESD | 1:3~1:6 | Negative | Online Inquiry |
KO29748 | MESD Knockout cell line (A549) | Human | MESD | 1:3~1:4 | Negative | Online Inquiry |
MESD Gene Knockout Cell Lines are genetically modified cell lines that have been specifically engineered to lack the expression of the MESD gene. This gene plays a critical role in the modulation of the Wnt signaling pathway, which is integral to various cellular processes, including proliferation, differentiation, and development. By creating knockout models, researchers can investigate the biological functions of the MESD gene and how its absence influences cellular behavior and signaling cascades.
The key function of MESD Gene Knockout Cell Lines lies in their ability to facilitate the study of gene function and regulatory mechanisms in a controlled environment. These cell lines are produced using CRISPR-Cas9 technology, which allows for precise editing of the genome, resulting in the targeted disruption of the MESD gene. By employing these knockout lines, researchers can observe phenotypic changes and dissect the role of MESD in various biological processes, such as cancer progression, stem cell behavior, and developmental biology.
The scientific importance of MESD Gene Knockout Cell Lines extends beyond basic research; they hold significant applications in clinical settings, particularly in cancer research and regenerative medicine. Understanding how the loss of MESD impacts cellular functions can lead to the discovery of novel therapeutic targets for cancer treatment and result in improved strategies for regenerative therapies.
Compared to alternative methods, such as RNA interference or traditional knockout techniques, MESD Gene Knockout Cell Lines provide a more stable and permanent solution for gene disruption, ensuring consistent experimental results. This reliability is essential for producing reproducible data and advancing biological understanding within the scientific community.
Researchers and clinicians will find value in MESD Gene Knockout Cell Lines as they unlock pathways to new discoveries, facilitate targeted therapeutic developments, and enhance the overall understanding of gene function in health and disease. Our company specializes in providing high-quality biological products designed to meet the rigorous demands of life science research, and we are committed to supporting the scientific community with innovative solutions that drive progress.
Please note that all services are for research use only. Not intended for any clinical use.
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