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MEOX2 Knockout Cell Lines

Gene: MEOX2

Official Full Name: mesenchyme homeobox 2provided by HGNC

Gene Summary: This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09551 MEOX2 Knockout cell line (HEK293) Human MEOX2 1:3~1:6 Negative Online Inquiry

Background

MEOX2 Gene Knockout Cell Lines are specialized cell lines engineered to have a targeted deletion of the MEOX2 gene, which is known to play a crucial role in various developmental processes, particularly in mesodermal and axial patterning. These knockout cell lines enable researchers to investigate the functional implications of MEOX2 loss, providing valuable insights into its contributions to cellular differentiation, embryonic development, and associated pathologies.

The key mechanism through which these knockout cell lines operate lies in the precise CRISPR/Cas9-mediated gene editing technology employed to create them. By abrogating the expression of the MEOX2 gene, researchers can observe the phenotypic and molecular consequences of its absence, thereby elucidating the biological pathways influenced by MEOX2. This allows for a deeper understanding of its role in developmental biology and its potential implications in diseases such as congenital malformations and certain cancers.

From a scientific perspective, MEOX2 Gene Knockout Cell Lines find applications in both basic and translational research. They serve as an essential model for examining gene function, drug screening, and the development of regenerative medicine strategies. By utilizing these cell lines, clinicians and researchers can better understand disease mechanisms and test therapeutic interventions.

One of the primary advantages of using MEOX2 Gene Knockout Cell Lines is their specificity and reliability compared to traditional knockout methods. The use of CRISPR technology not only ensures high efficiency in gene editing but also minimizes off-target effects, offering precise control over experimental conditions. Additionally, these cell lines are readily available for quick integration into existing research pipelines.

For researchers and clinicians invested in the fields of genetics and developmental biology, MEOX2 Gene Knockout Cell Lines represent a transformative tool that enhances the quality and depth of scientific inquiry. By choosing our product, users benefit from a culmination of our extensive expertise in cellular and molecular biology, ensuring they receive cutting-edge technology that bolsters their research capabilities.

Please note that all services are for research use only. Not intended for any clinical use.

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