Gene: MEIOB
Official Full Name: meiosis specific with OB-foldprovided by HGNC
Gene Summary: Predicted to enable chromatin binding activity; single-stranded DNA 3'-5' DNA exonuclease activity; and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination; fertilization; and meiotic nuclear division. Located in nucleus. Implicated in primary ovarian insufficiency and spermatogenic failure 22. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21145 | MEIOB Knockout cell line (A549) | Human | MEIOB | 1:3~1:4 | Negative | Online Inquiry |
MEIOB Gene Knockout Cell Lines are specialized cell lines engineered to lack the MEIOB gene, which is crucial for meiosis and gametogenesis. This product is designed to facilitate the study of meiosis-related biological mechanisms and offers a powerful tool for researchers exploring reproductive biology and genetic disorders. By utilizing CRISPR-Cas9 technology, these cell lines have been developed to ensure targeted disruption of the MEIOB gene, allowing for precise examination of the gene’s functionality and its role in cellular processes.
The primary function of MEIOB Gene Knockout Cell Lines is to enable scientists to investigate the cellular and molecular pathways implicated in meiotic progression. Researchers can analyze the phenotype of these knockout cells to understand better the effects of MEIOB deficiency on gamete formation, DNA repair, and chromosome segregation. This insight is invaluable for advancing knowledge in fields such as reproductive health, developmental biology, and genetic engineering.
In both research and clinical settings, MEIOB knockout models can facilitate the evaluation of novel therapeutic strategies for infertility and gametogenic disorders, thus holding significant clinical relevance. They serve as robust platforms for drug discovery and genetic studies, particularly in elucidating the mechanisms of male infertility linked to compromised spermatogenesis.
One of the key advantages of MEIOB Gene Knockout Cell Lines compared to alternative models is their specific and targeted disruption of the MEIOB gene, which minimizes off-target effects often observed in other models. Additionally, these cell lines provide consistent and reproducible results, making them an ideal choice for rigorous scientific investigation.
For researchers, clinicians, and biotechnologists, MEIOB Gene Knockout Cell Lines are invaluable for their potential to uncover the underlying genetics of meiosis and its related disorders. They provide critical insights that can lead to breakthroughs in understanding reproductive health and the development of targeted therapies.
Our company prides itself on its commitment to delivering high-quality biological products backed by robust scientific research. With our team of expert biologists and cutting-edge facilities, we strive to provide researchers with reliable tools that elevate their investigations and foster innovation in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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