Gene: MEI1
Official Full Name: meiotic double-stranded break formation protein 1provided by HGNC
Gene Summary: Predicted to be involved in meiosis I. Predicted to act upstream of or within germ cell development; meiotic nuclear division; and meiotic spindle organization. Implicated in gestational trophoblastic neoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22093 | MEI1 Knockout cell line (HeLa) | Human | MEI1 | 1:3~1:6 | Negative | Online Inquiry |
MEI1 Gene Knockout Cell Lines are genetically engineered cell lines in which the MEI1 gene has been selectively inactivated, providing a powerful tool for studying the role of this gene in biological processes and disease mechanisms. The MEI1 gene is known to play a crucial role in meiosis, particularly in the formation of meiosis-specific proteins and the regulation of meiotic recombination. By knocking out this gene, researchers can investigate the downstream effects on cellular processes, enabling insights into the implications of meiotic dysfunction and its potential links to infertility and genomic instability.
The mechanism underlying the utility of these knockout cell lines involves the absence of the MEI1 gene, which allows for the observation of phenotypic changes and alterations in cellular behavior in a controlled environment. This enables researchers to pinpoint specific pathways influenced by MEI1, facilitating the understanding of meiotic progression and its impact on gametogenesis.
In terms of scientific relevance, MEI1 Gene Knockout Cell Lines can significantly advance research in reproductive biology, genetics, and developmental biology, providing a model for studying conditions such as aneuploidy and its consequences. Additionally, they hold potential for applications in drug development, where understanding the role of meiosis in cancer cell proliferation may open up novel therapeutic avenues.
Compared to traditional methods of studying gene function, such as RNA interference or overexpression systems, MEI1 knockout cell lines offer a more permanent and stable alteration, yielding reproducible results and providing clarity in the interpretation of gene function. The specificity of these cell lines minimizes off-target effects often associated with alternative techniques, adding to the robustness of experimental outcomes.
For researchers and clinicians looking to deepen their understanding of meiotic mechanisms and associated disorders, the availability of MEI1 Gene Knockout Cell Lines is invaluable. They provide a versatile platform for experimental investigations while assisting in the development of therapeutics aimed at addressing fertility issues and genetic disorders.
With a commitment to advancing genetic research, our company specializes in providing high-quality genetic tools, including these innovative gene knockout cell lines, to empower scientists in their quest for knowledge and therapeutic breakthroughs.
Please note that all services are for research use only. Not intended for any clinical use.
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