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MED25 Knockout Cell Lines

Gene: MED25

Official Full Name: mediator complex subunit 25provided by HGNC

Gene Summary: This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq, Apr 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25636 MED25 Knockout cell line (HeLa) Human MED25 1:3~1:6 Negative Online Inquiry
KO25637 MED25 Knockout cell line (HCT 116) Human MED25 1:2~1:4 Negative Online Inquiry
KO25638 MED25 Knockout cell line (HEK293) Human MED25 1:3~1:6 Negative Online Inquiry
KO25639 MED25 Knockout cell line (A549) Human MED25 1:3~1:4 Negative Online Inquiry

Background

MED25 Gene Knockout Cell Lines represent a groundbreaking tool in functional genomics, engineered to facilitate in-depth studies of gene function and regulation, particularly pertaining to the MED25 gene. MED25 encodes a key subunit of the Mediator complex, which plays an essential role in conveying signals from transcription factors to the RNA polymerase II machinery, ultimately influencing gene expression. By employing CRISPR/Cas9 technology, these knockout cell lines provide a reliable means to ablate MED25 expression, thereby allowing researchers to assess the downstream effects on signaling pathways, phenotypic characteristics, and cellular responses.

The mechanistic insight provided by MED25 gene knockout cell lines is invaluable in both basic and applied research contexts. Researchers can elucidate the role of MED25 in various physiological processes, such as development, metabolism, and disease models, especially in cancer and neurodegenerative disorders. Moreover, these cell lines support high-throughput screening applications, enabling advanced pharmacological studies aimed at drug discovery and therapeutic development.

What sets our MED25 Gene Knockout Cell Lines apart from alternatives is their validated performance and reproducibility across different experimental conditions. Unlike transient knockdown approaches, these stable cell lines offer a more permanent solution for studying gene function, reducing variability in results. Furthermore, our optimized culture protocols and user-friendly product support enhance ease of use, allowing users to focus on their research objectives.

In an era where precision medicine and genetic research are paramount, these cell lines represent a significant asset for clinicians and researchers alike, enabling them to explore new avenues in targeted therapies and gene-based diagnostics. Our company boasts a strong legacy in the development of high-quality biological products, ensuring that we deliver cutting-edge tools that advance scientific inquiry and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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