Gene: MED10
Official Full Name: mediator complex subunit 10provided by HGNC
Gene Summary: MED10 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25063 | MED10 Knockout cell line (HeLa) | Human | MED10 | 1:3~1:6 | Negative | Online Inquiry |
KO25064 | MED10 Knockout cell line (HCT 116) | Human | MED10 | 1:2~1:4 | Negative | Online Inquiry |
KO25065 | MED10 Knockout cell line (HEK293) | Human | MED10 | 1:3~1:6 | Negative | Online Inquiry |
KO25066 | MED10 Knockout cell line (A549) | Human | MED10 | 1:3~1:4 | Negative | Online Inquiry |
MED10 Gene Knockout Cell Lines are specialized cellular models that have been meticulously engineered to disrupt the MED10 gene, a crucial component of the Mediator complex involved in transcription regulation. By systematically removing this gene, the MED10 knockout cell lines provide researchers with a valuable tool for investigating the functional role of MED10 in various biological processes, including gene expression, cell differentiation, and response to extracellular signals.
The core mechanism by which these cell lines operate involves the loss of function of the MED10 protein, leading to altered transcriptional activity of a wide array of genes. This disruption enables scientists to elucidate the pathways and interactions related to cell growth, cancer progression, and metabolic disorders. Through advanced CRISPR/Cas9 techniques, these cell lines exhibit high efficiency and specificity in gene editing, providing a reliable platform for functional genomics studies.
The scientific importance of MED10 Gene Knockout Cell Lines cannot be overstated, as they offer insights into the intricacies of gene regulation and its implications in various diseases, making them a critical resource in both basic and applied biomedical research. Their application spans across fundamental research, drug discovery, and therapeutic development, thereby facilitating advancements in understanding cancer biology, cardiovascular diseases, and metabolic syndromes.
What sets the MED10 Gene Knockout Cell Lines apart from conventional alternatives such as RNA interference or overexpression systems is their ability to create a stable and heritable genetic alteration without the residual effects from transient methods. Additionally, these knockout models allow for the precise investigation of gene functions in a context-specific manner, offering a significant advantage in obtaining reproducible results.
For researchers and clinicians alike, MED10 Gene Knockout Cell Lines represent an invaluable asset in the quest to unravel the complexities of gene function and its impact on human health. The availability of these cell lines enhances the potential for novel therapeutic strategies and provides a robust framework for translational research.
Our company prides itself on its commitment to delivering high-quality biological products, including cutting-edge gene knockout models that empower the scientific community to push the boundaries of knowledge in genomics and molecular biology. With an emphasis on innovation and reliability, we stand as a trusted partner in your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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