Gene: MCIDAS
Official Full Name: multiciliate differentiation and DNA synthesis associated cell cycle proteinprovided by HGNC
Gene Summary: This gene encodes a member of the geminin family of proteins. The encoded nuclear protein is required for the generation of multiciliated cells in respiratory epithelium. Mutations in this gene cause a rare mucociliary clearance disorder associated with recurring respiratory infections in human patients, known as reduced generation of multiple motile cilia (RGMC). [provided by RefSeq, Sep 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16293 | MCIDAS Knockout cell line (HeLa) | Human | MCIDAS | 1:3~1:6 | Negative | Online Inquiry |
KO16294 | MCIDAS Knockout cell line (HCT 116) | Human | MCIDAS | 1:2~1:4 | Negative | Online Inquiry |
KO16295 | MCIDAS Knockout cell line (HEK293) | Human | MCIDAS | 1:3~1:6 | Negative | Online Inquiry |
KO16296 | MCIDAS Knockout cell line (A549) | Human | MCIDAS | 1:3~1:4 | Negative | Online Inquiry |
MCIDAS Gene Knockout Cell Lines are expertly engineered human cell lines that have been specifically modified to lack the expression of the MCIDAS gene, which plays a critical role in cellular processes such as proliferation, differentiation, and oncogenesis. These cell lines serve as invaluable tools for researchers seeking to elucidate the molecular pathways and biological functions that are governed by the MCIDAS gene. By creating a precise gene knockout, scientists can investigate the effects of eliminating this gene, facilitating a deeper understanding of its contributions to various cellular phenomena.
The mechanisms of action underlying MCIDAS gene knockout involve techniques such as CRISPR-Cas9 or RNA interference, allowing for highly efficient and targeted gene disruption. This precision enables researchers to delineate the repercussions of gene loss, contributing to vital studies in developmental biology, cancer research, and regenerative medicine. The use of MCIDAS knockout lines can illuminate the gene's pivotal roles and associations with pathways like cell cycle regulation and epithelial-to-mesenchymal transition, which are critical in tumor metastasis.
The scientific importance of these cell lines extends to their applications in both basic and applied research settings. In a clinical context, understanding MCIDAS interactions can inform therapeutic strategies, particularly in cancers where this gene is implicated. Compared to alternative models, MCIDAS Gene Knockout Cell Lines provide an unprecedented level of specificity and relevance, allowing for more accurate models of human disease and the effects of potential therapies.
For researchers and clinicians alike, the advantages of utilizing MCIDAS Gene Knockout Cell Lines include reliable genetic manipulation, reproducible experimental results, and the facilitation of high-throughput screening for drug discovery. Furthermore, by opting for this product, users access a meticulously characterized resource that assures credibility and encourages seamless integration into ongoing research projects.
In summary, our company is dedicated to advancing the field of biotechnology by providing high-quality, precision-engineered cell lines like the MCIDAS Gene Knockout Cell Lines, backed by expertise in molecular genetics and a commitment to supporting groundbreaking scientific research.
Please note that all services are for research use only. Not intended for any clinical use.
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