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MAT2B Knockout Cell Lines

Gene: MAT2B

Official Full Name: methionine adenosyltransferase 2 non-catalytic beta subunitprovided by HGNC

Gene Summary: The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04532 MAT2B Knockout cell line (HeLa) Human MAT2B 1:3~1:6 Negative Online Inquiry
KO04533 MAT2B Knockout cell line (HCT 116) Human MAT2B 1:2~1:4 Negative Online Inquiry
KO04534 MAT2B Knockout cell line (HEK293) Human MAT2B 1:3~1:6 Negative Online Inquiry
KO04535 MAT2B Knockout cell line (A549) Human MAT2B 1:3~1:4 Negative Online Inquiry

Background

MAT2B Gene Knockout Cell Lines are genetically engineered cells that have undergone targeted gene disruption of the MAT2B gene, which encodes a critical component involved in methionine metabolism and redox balance. This advanced biological product allows researchers to study the implications of MAT2B gene dysfunction in various physiological and pathological contexts, including neurological disorders and cancer.

The key functions of MAT2B Gene Knockout Cell Lines revolve around their ability to mimic the molecular alterations seen in disease states. By eliminating the expression of MAT2B, these cell lines serve as invaluable tools to elucidate the role of this gene in cellular signaling, metabolism, and overall cell health. Researchers can utilize these cell lines to investigate the downstream effects of gene loss, including changes in homocysteine levels, oxidative stress, and methylation processes.

The scientific importance of MAT2B Gene Knockout Cell Lines is underscored by their applications in both basic research and clinical settings. They facilitate in-depth studies on the pharmacological targeting of methionine metabolism and aid in the identification of potential therapeutic agents for diseases linked to MAT2B dysregulation. Moreover, they contribute to the broader understanding of metabolic syndromes, providing insights into molecular pathways that are relevant for drug development.

One of the unique selling points of MAT2B Gene Knockout Cell Lines is their precision in gene editing, ensuring reproducibility and reliability in experimental results. Unlike alternative approaches, these knockout lines reflect genuine gene loss, allowing for more accurate modeling of disease mechanisms. Furthermore, the availability of these cell lines supports a streamlined research process, as they are readily accessible and offer consistent performance across various experimental conditions.

For researchers, clinicians, and biotechnology firms, MAT2B Gene Knockout Cell Lines represent a powerful resource that elevates the potential for groundbreaking discoveries. By incorporating these cell lines into studies, users can enhance their understanding of molecular disease mechanisms and drive forward the research necessary for developing innovative therapeutic strategies.

Our company specializes in providing high-quality biological products tailored to meet the evolving needs of the research community. With our commitment to scientific excellence and innovation, we ensure that each offering, including MAT2B Gene Knockout Cell Lines, is backed by rigorous validation and support, empowering researchers to achieve their scientific goals effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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