Gene: MARK3
Official Full Name: microtubule affinity regulating kinase 3provided by HGNC
Gene Summary: The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36701 | MARK3 Knockout cell line (HeLa) | Human | MARK3 | 1:3~1:6 | Negative | Online Inquiry |
KO36702 | MARK3 Knockout cell line (HCT 116) | Human | MARK3 | 1:2~1:4 | Negative | Online Inquiry |
KO36703 | MARK3 Knockout cell line (HEK293) | Human | MARK3 | 1:3~1:6 | Negative | Online Inquiry |
KO36704 | MARK3 Knockout cell line (A549) | Human | MARK3 | 1:3~1:4 | Negative | Online Inquiry |
MARK3 Gene Knockout Cell Lines are a state-of-the-art biological product designed for cellular and molecular biology research, specifically aimed at investigating the role of the MARK3 gene in various physiological and pathological processes. These genetically modified cell lines are created using CRISPR/Cas9 technology, enabling precise and efficient deletion of the MARK3 gene to generate knockout models that facilitate the study of gene function and related signaling pathways.
The MARK3 gene is known to play a crucial role in regulating signal transduction and microtubule dynamics, making these cell lines invaluable for elucidating its contributions to cellular processes such as cell division, migration, and response to stress. By examining the alterations in cellular behavior in response to MARK3 knockout, researchers can gain insights into diseases where altered microtubule dynamics are implicated, including cancer and neurodegenerative disorders.
One of the significant advantages of our MARK3 Gene Knockout Cell Lines is their high specificity and reliability, achieved through rigorous validation processes that confirm the efficient knockout of the target gene. Compared to alternative models, such as chemical inhibition or transient knockdown strategies, these stable knockout cell lines offer consistent and reproducible experimental conditions, making them ideal for longitudinal studies.
This product is particularly valuable to researchers and clinicians focused on understanding complex signaling networks and developing targeted therapies. The ability to create a controlled environment where MARK3 is absent allows for unambiguous interpretations of gene function, thereby accelerating the discovery of potential therapeutic strategies.
Our company brings decades of expertise in genetic engineering and cell line development to ensure that the MARK3 Gene Knockout Cell Lines maintain the highest levels of quality and scientific integrity. By choosing our product, researchers gain access to innovative tools that support cutting-edge discoveries in biological research and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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