Gene: MARK2
Official Full Name: microtubule affinity regulating kinase 2provided by HGNC
Gene Summary: This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38048 | MARK2 Knockout cell line (HeLa) | Human | MARK2 | 1:3~1:6 | Negative | Online Inquiry |
KO38049 | MARK2 Knockout cell line (HCT 116) | Human | MARK2 | 1:2~1:4 | Negative | Online Inquiry |
KO38050 | MARK2 Knockout cell line (HEK293) | Human | MARK2 | 1:3~1:6 | Negative | Online Inquiry |
KO38051 | MARK2 Knockout cell line (A549) | Human | MARK2 | 1:3~1:4 | Negative | Online Inquiry |
MARK2 Gene Knockout Cell Lines are a revolutionary biological tool designed for precise gene function studies and protein pathway analysis. Specifically, these cell lines have undergone targeted gene knockout of the MARK2 gene, which encodes a serine/threonine kinase implicated in various cellular processes, including cell polarity, mitosis, and neurogenesis. By employing CRISPR-Cas9 technology, these knockout lines facilitate the exploration of MARK2's role in cellular signaling pathways, allowing researchers to observe the consequences of its absence on cell behavior.
The primary function of MARK2 Gene Knockout Cell Lines is to provide a reliable and reproducible platform for studying the effects of gene inactivation. Upon loss of MARK2 expression, researchers can analyze alterations in protein interactions, signal transduction cascades, and metabolic pathways, illuminating the gene's functions and its impact on diseases, particularly neurodegenerative disorders and cancers.
In scientific research and clinical settings, these cell lines offer an essential resource for functional genomics, drug discovery, and personalized medicine. They are instrumental in validating therapeutic targets and understanding genetic contributions to disease, enabling advancements in molecular therapeutics and innovative treatment philosophies.
What sets MARK2 Gene Knockout Cell Lines apart from alternative products is their ready-to-use format and extensive characterization, ensuring high-quality performance, ease of handling, and consistency in experimental outcomes. The specificity of the MARK2 gene knockout mitigates off-target effects, providing researchers with accurate insights that are often lacking in traditional methods.
For researchers, clinicians, and biotech companies, these cell lines represent a valuable tool for dissecting complex biological pathways and advancing therapeutic strategies. By utilizing MARK2 Gene Knockout Cell Lines, users gain not only a powerful model for investigation but also contribute to the broader knowledge of gene function and disease mechanisms.
At [Company Name], we pride ourselves on our expertise in delivering high-quality biological products that empower researchers to push the boundaries of scientific discovery. Our commitment to innovation ensures that products like the MARK2 Gene Knockout Cell Lines significantly enhance research capabilities and foster the advancement of therapeutic solutions.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.