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MAPKAP1 Knockout Cell Lines

Gene: MAPKAP1

Official Full Name: MAPK associated protein 1provided by HGNC

Gene Summary: This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09083 MAPKAP1 Knockout cell line (HeLa) Human MAPKAP1 1:3~1:6 Negative Online Inquiry
KO09084 MAPKAP1 Knockout cell line (HCT 116) Human MAPKAP1 1:2~1:4 Negative Online Inquiry
KO09085 MAPKAP1 Knockout cell line (HEK293) Human MAPKAP1 1:3~1:6 Negative Online Inquiry
KO09086 MAPKAP1 Knockout cell line (A549) Human MAPKAP1 1:3~1:4 Negative Online Inquiry

Background

MAPKAP1 Gene Knockout Cell Lines are specialized cellular models engineered to silence the MAPKAP1 gene, which encodes the mitogen-activated protein kinase-associated protein 1. This product is invaluable for researchers studying the intricate networks of cellular signaling pathways involved in stress responses, inflammatory processes, and cellular proliferation. By utilizing gene knockout techniques, these cell lines provide a robust platform for examining the functional consequences of MAPKAP1 deficiency, thereby elucidating its role in various biological processes and diseases.

The key function of these cell lines lies in their ability to demonstrate the direct impact of MAPKAP1 absence on cellular responses to stimuli. Through loss-of-function studies, researchers can investigate downstream signaling alterations and the consequent changes in gene expression, protein interactions, and overall cellular behavior. This mechanism enables a deeper understanding of the MAPK signaling cascade, particularly in relation to its involvement in cancer, cardiovascular diseases, and immune responses.

In a research or clinical setting, MAPKAP1 gene knockout cell lines are pivotal for drug discovery and development, offering insights into potential therapeutic targets. They empower scientists to explore the molecular underpinnings of diseases influenced by MAPKAP1, facilitating the identification of biomarkers and novel treatment strategies.

What sets these cell lines apart from alternative models is their precision and reliability, allowing for reproducible results that are critical for rigorous scientific inquiry. Furthermore, these knockout lines are meticulously validated, ensuring that they provide a true representation of MAPKAP1 dysfunction without off-target effects.

For clinicians and researchers, investing in MAPKAP1 gene knockout cell lines translates into enhanced experimental accuracy and the ability to generate impactful insights that can drive innovation in therapeutics. Our company prides itself on offering high-quality biological products backed by extensive research and expertise in genetic engineering. We are committed to equipping the scientific community with tools that facilitate significant advancements in biotechnology and biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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