Gene: MAN2A2
Official Full Name: mannosidase alpha class 2A member 2provided by HGNC
Gene Summary: Predicted to enable alpha-mannosidase activity. Predicted to be involved in N-glycan processing. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36732 | MAN2A2 Knockout cell line (HeLa) | Human | MAN2A2 | 1:3~1:6 | Negative | Online Inquiry |
KO36733 | MAN2A2 Knockout cell line (HCT 116) | Human | MAN2A2 | 1:2~1:4 | Negative | Online Inquiry |
KO36734 | MAN2A2 Knockout cell line (HEK293) | Human | MAN2A2 | 1:3~1:6 | Negative | Online Inquiry |
KO36735 | MAN2A2 Knockout cell line (A549) | Human | MAN2A2 | 1:3~1:4 | Negative | Online Inquiry |
MAN2A2 Gene Knockout Cell Lines are a specialized tool designed for research in genetic manipulation and cellular biology, specifically targeting the MAN2A2 gene, which encodes a crucial enzyme involved in glycan processing. These knockout cell lines have been engineered to lack the functional MAN2A2 gene, providing researchers with a unique platform to study the effects of this gene's absence on cellular processes, including glycosylation pathways, protein stability, and metabolic functions.
The primary function of MAN2A2 Gene Knockout Cell Lines is to facilitate the investigation of mannose 6-phosphate-specific pathways, thereby elucidating their roles in cell signaling, immunity, and disease pathology. By leveraging CRISPR-Cas9 technology for precise gene editing, researchers can focus on studying the downstream effects of MAN2A2 depletion, contribute to understanding glycoprotein synthesis, and explore therapeutic targets for diseases related to glycan abnormalities.
The scientific importance of these cell lines extends to various research fields, including cancer biology, immunology, and metabolic disorders, making them invaluable for both basic and applied research. In clinical settings, understanding the functions disrupted by MAN2A2 knockout can pave the way for innovations in gene therapy and precision medicine.
Compared to alternative cell lines, MAN2A2 Gene Knockout Cell Lines offer uniquely tailored features, such as verified genetic alterations and reproducibility of results, ensuring reliable experimentation outcomes. Unlike unspecific knockdowns or overexpression systems, these knockout lines provide a definitive model to discern the precise impact of MAN2A2 absence.
Researchers and clinicians will find significant value in this product, as it not only enhances their experimental repertoire but also allows for a deeper understanding of the gene's implications in health and disease. Access to our MAN2A2 Gene Knockout Cell Lines represents a commitment to advancing scientific knowledge and therapeutic advancements.
Our company is dedicated to providing high-quality biological products and tools backed by rigorous scientific validation, empowering researchers to unlock new dimensions in cellular and genetic research.
Please note that all services are for research use only. Not intended for any clinical use.
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