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MAL2 Knockout Cell Lines

Gene: MAL2

Official Full Name: mal, T cell differentiation protein 2provided by HGNC

Gene Summary: This gene encodes a multispan transmembrane protein belonging to the MAL proteolipid family. The protein is a component of lipid rafts and, in polarized cells, it primarily localizes to endosomal structures beneath the apical membrane. It is required for transcytosis, an intracellular transport pathway used to deliver membrane-bound proteins and exogenous cargos from the basolateral to the apical surface. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30793 MAL2 Knockout cell line (HeLa) Human MAL2 1:3~1:6 Negative Online Inquiry
KO30794 MAL2 Knockout cell line (HCT 116) Human MAL2 1:2~1:4 Negative Online Inquiry
KO30795 MAL2 Knockout cell line (HEK293) Human MAL2 1:3~1:6 Negative Online Inquiry

Background

MAL2 Gene Knockout Cell Lines are a specialized biological research tool designed to facilitate the study of the MAL2 gene’s role in cellular processes and disease mechanisms. These cell lines have been engineered to achieve a targeted deletion of the MAL2 gene, which encodes for a protein implicated in various physiological processes, including cell signaling and membrane dynamics. By eliminating MAL2 expression, researchers can investigate its functions and the downstream biological pathways it influences, elucidating critical mechanistic insights into cellular behavior.

The key function of these knockout cell lines lies in their ability to mimic loss-of-function conditions, making them invaluable for studying gene-specific effects. Researchers can utilize these models to assess changes in cellular responses, proliferation, differentiation, and apoptosis, thereby spotlighting the role of MAL2 in various biological contexts. Furthermore, MAL2 knockout cell lines serve as powerful tools in drug discovery, providing a platform to evaluate therapeutic candidates targeting related pathways.

From a scientific perspective, these cell lines are crucial for advancing research in oncology, immunology, and neurobiology, particularly in understanding tumorigenesis, immune response modulation, and cellular stress responses. Their application in clinical settings can potentially pave the way for novel therapeutic strategies.

One of the standout advantages of our MAL2 Gene Knockout Cell Lines is their high-quality, consistent genetic background, which surpasses many alternative models that may exhibit variable knockout efficiency. Our product is rigorously validated to ensure reliable performance across multiple experiments, allowing researchers to draw meaningful conclusions with confidence.

For researchers and clinicians aiming to deepen their understanding of the intricate roles that specific genes play in health and disease, our MAL2 Gene Knockout Cell Lines offer an unparalleled resource. They empower users to uncover new biological insights that could lead to groundbreaking therapeutic innovations. With extensive expertise in genetic engineering and cell biology, our company is committed to providing cutting-edge products that accelerate research advancements and enhance scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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