Gene: MAGOHB
Official Full Name: mago homolog B, exon junction complex subunitprovided by HGNC
Gene Summary: Enables RNA binding activity. Involved in mRNA splicing, via spliceosome and nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Located in nucleus. Part of U2-type catalytic step 1 spliceosome; U2-type precatalytic spliceosome; and exon-exon junction subcomplex mago-y14. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16375 | MAGOHB Knockout cell line (HeLa) | Human | MAGOHB | 1:3~1:6 | Negative | Online Inquiry |
KO16376 | MAGOHB Knockout cell line (HCT 116) | Human | MAGOHB | 1:2~1:4 | Negative | Online Inquiry |
KO16377 | MAGOHB Knockout cell line (HEK293) | Human | MAGOHB | 1:3~1:6 | Negative | Online Inquiry |
KO16378 | MAGOHB Knockout cell line (A549) | Human | MAGOHB | 1:3~1:4 | Negative | Online Inquiry |
MAGOHB Gene Knockout Cell Lines represent a cutting-edge tool for gene function studies and therapeutic development, crafted for researchers aiming to explore gene roles in various biological processes. These cell lines are specifically engineered to lack the MAGOHB gene, a critical component involved in RNA splicing and various cellular mechanisms. By utilizing precise gene-editing techniques such as CRISPR/Cas9, MAGOHB knockout cell lines facilitate the investigation of gene interactions, cellular pathways, and the impacts of gene silencing on cellular physiology.
The primary function of MAGOHB knockout cell lines is to elucidate the gene's contribution to cellular functions, including proliferation, differentiation, and response to stressors. Researchers can study how the absence of MAGOHB affects mRNA stability and translation efficiency, providing valuable insights into its role in disease mechanisms, particularly in cancers where splicing dysregulation is implicated. This product is vital in both basic research and translational studies, influencing the development of targeted therapies based on a deeper understanding of MAGOHB's involvement in pathophysiological conditions.
What sets MAGOHB Gene Knockout Cell Lines apart from alternative models is their ease of use, robust reproducibility, and validation support. These cell lines are pre-characterized to ensure consistency, significantly reducing the time researchers spend verifying experimental conditions. Additionally, our product comes with a comprehensive user manual and technical support, enhancing the user experience for those conducting complex experiments.
For researchers and clinicians focusing on gene functionality and novel therapeutic strategies, MAGOHB Gene Knockout Cell Lines offer unparalleled value, equipping them with a reliable model system to explore gene therapies and investigate gene-environment interactions. This innovative product underscores our commitment to advancing scientific research with reliable, high-quality biological products tailored to meet the needs of the research community and clinical applications. Our expertise in cellular biology enables us to bring forward solutions that facilitate groundbreaking discoveries and therapeutic advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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