Gene: MAGI3
Official Full Name: membrane associated guanylate kinase, WW and PDZ domain containing 3provided by HGNC
Gene Summary: Predicted to enable frizzled binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within positive regulation of JUN kinase activity. Located in cell junction. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO08774 | MAGI3 Knockout cell line (HeLa) | Human | MAGI3 | 1:3~1:6 | Negative | Online Inquiry |
KO08775 | MAGI3 Knockout cell line (HCT 116) | Human | MAGI3 | 1:2~1:4 | Negative | Online Inquiry |
KO08776 | MAGI3 Knockout cell line (HEK293) | Human | MAGI3 | 1:3~1:6 | Negative | Online Inquiry |
KO08777 | MAGI3 Knockout cell line (A549) | Human | MAGI3 | 1:3~1:4 | Negative | Online Inquiry |
MAGI3 Gene Knockout Cell Lines are specifically engineered cellular models used to study the functions and regulatory mechanisms of the MAGI3 gene, which is known to play a crucial role in various cellular processes, including cellular signaling, adhesion, and synapse formation. These knockout cell lines provide a potent tool for investigating the pathways and interactions affected by the loss of MAGI3, allowing researchers to elucidate its contributions to diseases such as cancer and neurological disorders.
The MAGI3 Gene Knockout Cell Lines function through a targeted CRISPR/Cas9 gene editing approach, effectively disrupting the MAGI3 gene, consequently enabling scientists to observe the resultant phenotypic and molecular changes. This mechanism not only confirms the role of MAGI3 in health and disease but also enables the exploration of compensatory pathways that might be activated in its absence.
The scientific importance of MAGI3 Gene Knockout Cell Lines extends to their applications across research and clinical settings, where they can be utilized for functional genomics, drug discovery, and the development of gene therapies. Their role in the study of various signal transduction pathways emphasizes their value in cancer research, neuroscience, and other fields requiring a deeper understanding of genetic contributions to disease.
Compared to alternative cell lines, MAGI3 Gene Knockout Cell Lines offer a specific focus on the MAGI3 gene, eliminating background variability and reducing experimental noise. This specificity enhances the reliability of experimental outcomes, ensuring that results are directly attributable to MAGI3’s functionality. Furthermore, they are developed to maintain crucial characteristics of wild-type cells, aiding in the translatability of findings to in vivo systems.
For researchers and clinicians seeking to deepen their understanding of MAGI3-related mechanisms, these knockout cell lines represent unparalleled value. They provide a unique opportunity to propel forward the understanding of complex biological interactions and disease mechanisms, translating insights into potential therapeutic avenues.
As a leader in the field of genetic engineering and biological products, our company is dedicated to providing high-quality, innovative solutions for researchers and clinicians. Our MAGI3 Gene Knockout Cell Lines stand as a testament to our commitment to advancing scientific inquiry and improving health outcomes through rigorous research tools.
Please note that all services are for research use only. Not intended for any clinical use.
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