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MAFB Knockout Cell Lines

Gene: MAFB

Official Full Name: MAF bZIP transcription factor Bprovided by HGNC

Gene Summary: The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03180 MAFB Knockout cell line (HeLa) Human MAFB 1:3~1:6 Negative Online Inquiry
KO03181 MAFB Knockout cell line (HEK293) Human MAFB 1:3~1:6 Negative Online Inquiry

Background

MAFB Gene Knockout Cell Lines are a specialized set of genetically engineered cell lines in which the MAFB gene has been precisely disrupted or “knocked out” through advanced gene editing techniques. This allows for the detailed study of the MAFB gene’s functions, particularly its roles in cellular processes such as differentiation, proliferation, and survival, especially in the context of hematopoietic and immune response pathways. By utilizing these knockout cell lines, researchers can elucidate the effects of MAFB deficiency on various signaling pathways and cellular behaviors, providing critical insights into its contributions to health and disease.

The key function of MAFB involves its role as a transcription factor that regulates the expression of target genes critical for normal cellular function. By manipulating these knockout cell lines, scientists can observe the resulting phenotypic changes, facilitating research into the pathological conditions associated with MAFB dysregulation, including developmental disorders and cancers. In clinical settings, understanding MAFB’s role may lead to novel therapeutic strategies targeting related signaling pathways, thereby enhancing patient outcomes.

Unique advantages of our MAFB Gene Knockout Cell Lines include their high specificity and reproducibility, achieved through precision gene editing technologies such as CRISPR/Cas9. Compared to traditional methods of gene manipulation that may produce off-target effects or variable results, our cell lines promise consistent and reliable data. This quality assures researchers and clinicians that their findings will be robust and reproducible, permitting deeper exploration into the molecular mechanisms linked to MAFB.

Research professionals will find considerable value in these knockout cell lines, as they open the doors for innovative studies that could unravel previously unexplored biological functions and lead to breakthroughs in understanding MAFB-related diseases. With expert scientists on our team and a dedication to quality research tools, our company stands at the forefront of providing advanced biological products that empower research and bolster the scientific community’s endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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