Gene: MACIR
Official Full Name: macrophage immunometabolism regulatorprovided by HGNC
Gene Summary: This gene, MACIR (previously known as C5orf30), has been associated with rheumatoid arthritis, functioning as a negative regulator of tissue damage and modulating the activity of synovial fibroblasts and macrophages. The encoded protein is highly conserved in vertebrate genomes but has no significant similarity to any other human protein. [provided by RefSeq, Dec 2019]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23770 | MACIR Knockout cell line (HeLa) | Human | MACIR | 1:3~1:6 | Negative | Online Inquiry |
KO23771 | MACIR Knockout cell line (HCT 116) | Human | MACIR | 1:2~1:4 | Negative | Online Inquiry |
KO23772 | MACIR Knockout cell line (HEK293) | Human | MACIR | 1:3~1:6 | Negative | Online Inquiry |
KO23773 | MACIR Knockout cell line (A549) | Human | MACIR | 1:3~1:4 | Negative | Online Inquiry |
MACIR Gene Knockout Cell Lines are specifically engineered cell lines that have undergone targeted gene disruption to study the effects of loss-of-function mutations on cellular processes. Utilizing advanced CRISPR-Cas9 technology, these cell lines enable researchers to dissect gene function by selectively inactivating specific genes, thereby facilitating the exploration of their role in various biological pathways and disease mechanisms.
The key function of MACIR Gene Knockout Cell Lines relies on their ability to provide a reliable and reproducible model for gene expression analysis. By knocking out genes of interest, scientists can observe resultant phenotypic changes and alterations in signaling pathways, helping illuminate the underlying biological mechanisms at play. The rapid generation of these knockout models allows for time-efficient experiments, making them essential tools in both academic research and pharmaceutical development.
Scientifically, MACIR Gene Knockout Cell Lines hold significant importance in various applications including functional genomics, drug discovery, and disease modeling. Their ability to mimic specific disease states by knocking out genes associated with conditions such as cancer and neurodegeneration makes them invaluable for therapeutic research and testing. In clinical settings, these models can guide the development of targeted therapies and personalized medicine approaches, ultimately leading to more effective treatments.
Compared to traditional gene editing methods, MACIR Gene Knockout Cell Lines offer an unparalleled level of precision and efficiency. Their user-friendly protocols and comprehensive validation simplify the experimental design process, allowing researchers to focus more on their scientific inquiries rather than the complexities of cell line generation. Additionally, the consistent quality and performance of these cell lines ensure reproducibility across experiments and laboratories.
In summary, MACIR Gene Knockout Cell Lines stand out as essential resources for researchers and clinicians aiming to unravel the complexities of gene function. With our company’s expertise in genetic engineering and commitment to providing high-quality biological products, we are proud to support scientific discovery and innovation through our cutting-edge offerings.
Please note that all services are for research use only. Not intended for any clinical use.
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