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Lox Knockout Cell Lines

Gene: Lox

Official Full Name: lysyl oxidaseprovided by MGI

Gene Summary: This gene encodes a precursor protein that belongs to the lysyl oxidase family of proteins. The secreted proprotein is proteolytically processed to an active mature peptide and a propeptide. This propeptide is thought to function in tumor suppression by inhibiting the Ras signaling pathway. The active enzyme plays a role in cross-linking of collagen and elastin and is essential for development of cardiovascular and respiratory systems, and development of skin and connective tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01230 Lox Knockout cell line (HT22) Mouse Lox Negative Online Inquiry

Background

Lox Gene Knockout Cell Lines are genetically engineered cell lines that utilize the Cre-lox recombination system to facilitate targeted gene knockout. This innovative technology allows researchers to selectively inactivate genes of interest, providing a powerful tool to study gene function and disease mechanisms. The Lox system relies on the specific recognition of loxP sites by the Cre recombinase enzyme, resulting in precise excision of genetic sequences. This method is advantageous for generating stable cell lines where the disruption of gene expression can be observed over time in various experimental conditions.

The key functions of Lox Gene Knockout Cell Lines lie in their ability to provide insights into gene interactions, cell signaling pathways, and the potential roles of specific genes in disease models. These cell lines are instrumental in preclinical research, enabling scientists to assess the effects of genetic modifications on cellular behavior, drug response, and phenotypic changes. Their high specificity and versatility make them invaluable in both in vitro studies and for developing transgenic animal models.

In comparison to traditional knockout techniques, Lox Gene Knockout Cell Lines offer enhanced precision and control, reducing off-target effects and enabling researchers to create more reliable models. The ability to study gene function in a more context-dependent manner is a significant advantage that facilitates deeper insights into cellular processes.

For researchers and clinicians, the value of Lox Gene Knockout Cell Lines extends beyond academic inquiry; they are essential for the identification of potential therapeutic targets and the development of gene-based therapies. By utilizing these sophisticated cell lines, users can accelerate their research timelines and improve the robustness of their findings.

Our company specializes in the development and production of high-quality biological products, backed by a team of experts dedicated to advancing scientific knowledge. With a commitment to innovation and customer support, we deliver solutions that empower researchers to unlock the complexities of gene function and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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