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LYPD6B Knockout Cell Lines

Gene: LYPD6B

Official Full Name: LY6/PLAUR domain containing 6Bprovided by HGNC

Gene Summary: Enables acetylcholine receptor regulator activity. Predicted to be located in extracellular region and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03433 LYPD6B Knockout cell line (HeLa) Human LYPD6B 1:3~1:6 Negative Online Inquiry
KO03434 LYPD6B Knockout cell line (HCT 116) Human LYPD6B 1:2~1:4 Negative Online Inquiry
KO03435 LYPD6B Knockout cell line (HEK293) Human LYPD6B 1:3~1:6 Negative Online Inquiry

Background

LYPD6B Gene Knockout Cell Lines comprise genetically modified cells designed to specifically disrupt the expression of the LYPD6B gene, which is involved in various neurological and immunological processes. These cell lines are crucial for researchers investigating the gene's functional contributions to cellular pathways and disease states, particularly in the context of inflammation and neurological disorders. The knockout approach involves the use of CRISPR-Cas9 or similar genome editing techniques, which facilitate precise deletions in the target gene, leading to an effective loss of function.

The primary function of LYPD6B gene knockout cell lines is to serve as a model for studying the gene's role in physiological and pathological conditions. By evaluating differences in cellular behavior, researchers can gain insights into the mechanisms by which LYPD6B regulates signaling pathways, receptor interactions, and overall cell signaling dynamics. This cellular understanding can further propel advancements in targeted therapies.

In terms of scientific importance, LYPD6B knockout models are pivotal for elucidating the gene's contributions to diseases where inflammation and immune response play a critical role, such as multiple sclerosis and various cancers. By utilizing these models, both academic and clinical researchers can tailor their investigations towards developing novel intervention strategies.

Compared to alternatives such as overexpression models or RNA interference approaches, LYPD6B gene knockout cell lines provide a more definitive and permanent disruption of the gene’s functionality. This allows for better examination of phenotypic changes without the confounding effects associated with partial or transient gene silencing.

The value of LYPD6B gene knockout cell lines to researchers and clinicians is underscored by their ability to produce reproducible and reliable data that can accelerate the understanding of disease mechanisms and therapeutic targets. By choosing our product, users are not only acquiring a robust experimental tool but also aligning themselves with a company dedicated to excellence in genetic engineering and cell line development. Our expertise ensures that every cell line we offer is rigorously validated, supporting researchers in their quest to unlock the mysteries of gene function and its implications in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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