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LYAR Knockout Cell Lines

Gene: LYAR

Official Full Name: Ly1 antibody reactiveprovided by HGNC

Gene Summary: Enables several functions, including DNA-binding transcription factor binding activity; identical protein binding activity; and transcription regulator inhibitor activity. Involved in several processes, including erythrocyte development; negative regulation of innate immune response; and regulation of DNA-templated transcription. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16406 LYAR Knockout cell line (HeLa) Human LYAR 1:3~1:6 Negative Online Inquiry
KO16407 LYAR Knockout cell line (HCT 116) Human LYAR 1:2~1:4 Negative Online Inquiry
KO16408 LYAR Knockout cell line (HEK293) Human LYAR 1:3~1:6 Negative Online Inquiry
KO16409 LYAR Knockout cell line (A549) Human LYAR 1:3~1:4 Negative Online Inquiry

Background

LYAR Gene Knockout Cell Lines are a cutting-edge tool designed for functional genomic studies, allowing researchers to elucidate the role of the LYAR gene in various biological processes and disease states. By employing CRISPR-Cas9 technology, these cell lines feature precise deletions within the LYAR gene, effectively disrupting its function. This knockout is instrumental for investigating the gene's involvement in cellular pathways, gene regulation, and its potential implications in conditions such as cancer and autoimmune disorders.

The key function of LYAR Gene Knockout Cell Lines lies in their ability to provide a controlled environment to study the effects of LYAR loss on cellular behavior. The mechanisms by which these cell lines operate entail the introduction of guide RNAs that target specific sequences within the LYAR gene, creating a double-strand break that, when repaired, results in targeted gene disruption. This creates an invaluable resource for scientists aiming to dissect pathways influenced by LYAR and to identify new therapeutic targets.

In both research and clinical settings, these knockout cell lines are vital for advancing our understanding of gene function and the molecular underpinnings of disease. They offer researchers the opportunity to assess cellular responses to various treatments, thus aiding in drug discovery and the development of novel therapeutic strategies.

What sets LYAR Gene Knockout Cell Lines apart from traditional models is their specificity and reliability. Unlike conventional gene silencing techniques, these lines provide a complete and permanent gene knockout, ensuring that observed phenotypes are directly attributable to the loss of LYAR function. Furthermore, our product is characterized by high transfection efficiency and reproducibility, allowing for consistent results across different experiments.

For researchers and clinicians, the value of LYAR Gene Knockout Cell Lines is evident in their application potential—from basic research to translational studies. They empower users to gain deeper insights into the molecular landscape of diseases, facilitate validation of therapeutic targets, and ultimately contribute to the advancement of precision medicine.

Our company is dedicated to providing high-quality biological products backed by extensive research and development expertise. With a focus on innovative cell line technology, we ensure that our offerings meet the rigorous demands of the scientific community, supporting advancements in health and disease understanding.

Please note that all services are for research use only. Not intended for any clinical use.

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