Home / LY6E Knockout Cell Lines

LY6E Knockout Cell Lines

Gene: LY6E

Official Full Name: lymphocyte antigen 6 family member Eprovided by HGNC

Gene Summary: This gene belongs to the human Ly6 gene family and encodes a glycosylphosphatidyl-inositol (GPI)-anchored cell surface protein. The protein plays an important role in T cell physiology, oncogenesis and immunological regulation. The protein is also involved in modulation of viral infection by coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2. [provided by RefSeq, Aug 2021]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36751 LY6E Knockout cell line (HeLa) Human LY6E 1:3~1:6 Negative Online Inquiry
KO36752 LY6E Knockout cell line (HCT 116) Human LY6E 1:2~1:4 Negative Online Inquiry
KO36753 LY6E Knockout cell line (HEK293) Human LY6E 1:3~1:6 Negative Online Inquiry
KO36754 LY6E Knockout cell line (A549) Human LY6E 1:3~1:4 Negative Online Inquiry

Background

LY6E Gene Knockout Cell Lines are specialized cellular models developed to lack the expression of the LY6E gene, which encodes a glycosylphosphatidylinositol (GPI)-anchored protein notably involved in immune system regulation and host-pathogen interactions. These cell lines are engineered utilizing CRISPR/Cas9 technology, providing precise editing capabilities that allow researchers to observe phenotypic changes and elucidate the cellular pathways regulated by LY6E.

The primary function of the LY6E Gene Knockout Cell Lines lies in their utility for investigating the role of LY6E in various biological processes, including immune responses to viral infections and cancer development. By inhibiting LY6E, researchers can explore potential compensatory mechanisms within the immune system and assess how the absence of this gene impacts cell signaling and behavior. These knockout models also serve as crucial tools for high-throughput screening assays in drug development, providing insight into new therapeutic targets.

The scientific importance of LY6E Gene Knockout Cell Lines extends to both fundamental research and clinical applications. In virology and immunology, they facilitate the understanding of pathogen evasion tactics and may inform vaccine development strategies. Furthermore, these cell lines are valuable for studying tumor biology, offering insights into tumor microenvironments and potential interactions between cancer cells and immune effectors.

What sets LY6E Gene Knockout Cell Lines apart from alternative models is their specificity and the reliability of CRISPR-mediated gene knockout. This precision reduces off-target effects, enhancing the robustness of experimental outcomes and providing dependable data for downstream applications. This product significantly enhances research capabilities, enabling scientists to obtain clearer insights while minimizing experimental variability associated with other less targeted models.

Researchers and clinicians seeking to advance their understanding of immune mechanisms and therapeutic interventions will find LY6E Gene Knockout Cell Lines invaluable in their work. The ability to dissect the role of LY6E more clearly can lead to breakthroughs in treatment strategies and a greater understanding of disease mechanisms.

Our company embodies extensive expertise in developing genetically engineered models for research applications. With a commitment to quality, we provide biological products that meet rigorous scientific standards to empower researchers across various fields.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.