Gene: LURAP1
Official Full Name: leucine rich adaptor protein 1provided by HGNC
Gene Summary: Involved in positive regulation of canonical NF-kappaB signal transduction and positive regulation of cytokine production. Located in cytosol and intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16424 | LURAP1 Knockout cell line (HEK293) | Human | LURAP1 | 1:3~1:6 | Negative | Online Inquiry |
LURAP1 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, specifically designed to facilitate the in-depth study of the LURAP1 gene's function and its implications in various biological processes. These genetically engineered cell lines have been created using CRISPR-Cas9 technology, which enables precise gene editing, allowing researchers to completely disrupt the LURAP1 gene. By knocking out this gene, scientists can investigate its contribution to cellular functions and its potential role in disease mechanisms.
The primary mechanism of LURAP1 gene knockout cell lines involves the targeted introduction of double-strand breaks in the LURAP1 gene, followed by cellular repair processes that typically result in insertions or deletions (indels). These indels lead to the production of non-functional LURAP1 transcripts, effectively silencing its expression. Such cell lines are invaluable for elucidating the biological pathways influenced by LURAP1 and have significant implications in cancer research, immune response studies, and other areas where LURAP1 activity is suspected to be crucial.
The scientific importance of these knockout cell lines lies in their versatile applications, particularly in drug development and therapeutic interventions where understanding the role of specific genes is essential. They allow researchers to model diseases more accurately, providing insights that drive innovative treatment strategies and improve clinical outcomes.
Compared to traditional gene disruption methods, LURAP1 gene knockout cell lines offer several distinct advantages. These include high specificity in gene targeting, reduced off-target effects, and the ability to generate stable, uniform cell populations for reproducible experimental results. Furthermore, the ease of use associated with CRISPR technology empowers researchers to conduct high-throughput studies without the complexities and inefficiencies of older techniques.
For researchers and clinicians alike, the value of LURAP1 gene knockout cell lines is evident. They no longer need to rely on less specific methods, allowing for greater confidence in experimental outcomes and paving the way for groundbreaking discoveries.
Our company specializes in providing high-quality, rigorously validated biological products, including gene knockout cell lines tailored for specialized research needs. With a commitment to supporting scientific advancement, we are dedicated to equipping researchers with the tools necessary to unlock the complexities of gene function and disease biology.
Please note that all services are for research use only. Not intended for any clinical use.
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