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LUM Knockout Cell Lines

Gene: LUM

Official Full Name: lumicanprovided by HGNC

Gene Summary: This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05192 LUM Knockout cell line (HeLa) Human LUM 1:3~1:6 Negative Online Inquiry
KO05193 LUM Knockout cell line (A549) Human LUM 1:3~1:4 Negative Online Inquiry

Background

LUM Gene Knockout Cell Lines represent a cutting-edge tool in genetic research, designed to facilitate the exploration of gene function and regulation. These cell lines are engineered through advanced CRISPR-Cas9 technology, which allows for precise gene editing, resulting in the complete disablement of specific target genes. The LUM Gene Knockout Cell Lines provide researchers with a reliable platform for studying gene expression, signaling pathways, and the impact of gene disruption on cellular behavior.

The primary mechanism through which these cell lines operate is the targeted disruption of genomic DNA, leading to loss-of-function mutations. This capability enables scientists to delineate the roles of particular genes in various biological processes, such as cell growth, differentiation, and apoptosis. In research settings, these cell lines are instrumental in elucidating the genetic underpinnings of diseases, including cancer and genetic disorders, thus contributing valuable insights into potential therapeutic targets.

LUM Gene Knockout Cell Lines stand out for their exceptional specificity and efficiency, offering researchers a streamlined process compared to traditional gene knockout methods. Unlike earlier technologies, LUM's offerings minimize off-target effects and provide consistent and reproducible results, which are critical for achieving high-quality scientific data. Additionally, the versatility of these cell lines allows for their adaptation across various model systems, making them suitable for a wide array of experimental conditions.

For researchers and clinicians, LUM Gene Knockout Cell Lines represent an invaluable asset in advancing biological understanding and therapeutic innovation. Their ease of use, combined with the high degree of genetic control they offer, enables users to accelerate their research timelines and enhance the overall quality of their findings.

With a commitment to excellence and innovation, our company excels in providing advanced biological products backed by robust scientific expertise. We are dedicated to supporting the research community with reliable and sophisticated tools that empower groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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