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LTK Knockout Cell Lines

Gene: LTK

Official Full Name: leukocyte receptor tyrosine kinaseprovided by HGNC

Gene Summary: The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36760 LTK Knockout cell line (HCT 116) Human LTK 1:2~1:4 Negative Online Inquiry
KO36761 LTK Knockout cell line (HEK293) Human LTK 1:3~1:6 Negative Online Inquiry

Background

LTK Gene Knockout Cell Lines are specifically engineered cellular models that have undergone targeted gene disruption to inactivate the LTK gene, which encodes for the leukocyte receptor tyrosine kinase. These cell lines serve as vital tools for elucidating the biological function of LTK in various cellular processes, including cell signaling, proliferation, and differentiation. By providing a substrate devoid of LTK function, researchers can better understand its role in pathophysiological conditions, such as certain cancers and immune disorders.

These cell lines operate on a robust mechanism of CRISPR-Cas9 technology, allowing for precise edits to the genome. The resulting knockout of LTK enables detailed investigations into downstream signaling pathways and interaction networks. This detailed characterization fosters advancements in therapeutic strategies targeted at modulating LTK-associated pathways, potentially leading to breakthroughs in targeted therapies and personalized medicine.

The scientific importance of LTK Gene Knockout Cell Lines cannot be overstated. They open avenues for high-throughput screening, elucidation of drug targets, and studies on receptor physiology. In clinical settings, these cell lines facilitate the development of novel therapeutics aimed at improving treatment outcomes in patients with LTK-related diseases.

What sets our LTK Gene Knockout Cell Lines apart from alternative models is their validated specificity and reproducibility. Each cell line undergoes rigorous testing to ensure consistent performance in experimental setups, significantly reducing variability in research outcomes. Furthermore, the availability of detailed user guides and customer support enhances the user experience.

For researchers and clinicians, these cell lines are invaluable assets that not only streamline experimental workflows but also provide insights that could lead to significant advancements in medical science. Our company is committed to delivering high-quality biological products, backed by our extensive expertise in genetic engineering and cellular biology, ensuring that you have the best tools at your disposal for your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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