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LRRC58 Knockout Cell Lines

Gene: LRRC58

Official Full Name: leucine rich repeat containing 58provided by HGNC

Gene Summary: Predicted to be involved in intracellular signal transduction. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03708 LRRC58 Knockout cell line (HeLa) Human LRRC58 1:3~1:6 Negative Online Inquiry
KO03709 LRRC58 Knockout cell line (HCT 116) Human LRRC58 1:2~1:4 Negative Online Inquiry
KO03710 LRRC58 Knockout cell line (HEK293) Human LRRC58 1:3~1:6 Negative Online Inquiry
KO03711 LRRC58 Knockout cell line (A549) Human LRRC58 1:3~1:4 Negative Online Inquiry

Background

LRRC58 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the leucine-rich repeat-containing protein 58 (LRRC58). These cell lines have been genetically engineered to have a complete knockout of the LRRC58 gene, allowing researchers to investigate the functional role of this gene in various biological processes, including immune response, cell signaling, and development. The knockout mechanism is achieved through advanced CRISPR/Cas9 technology, which enables precise edits to the genome, creating a reliable platform for functional assays.

The key function of the LRRC58 gene is its involvement in intracellular signaling pathways, particularly in relation to the immune system's response to pathogens. By utilizing the LRRC58 Gene Knockout Cell Lines, researchers can delineate the specific contributions of LRRC58 to cellular functions and explore its implications in diseases such as autoimmune disorders or cancer. The ability to observe phenotypic changes resulting from the absence of LRRC58 provides invaluable insights into target pathways and potential therapeutic interventions.

This product's scientific importance cannot be overstated, especially in research and clinical settings where understanding genetic contributions to disease is crucial. Compared to traditional cell lines with intact gene expression, LRRC58 knockout lines offer a unique opportunity to elucidate the consequences of gene loss, thus advancing our knowledge in genetic research and biomedicine.

One of the unique selling points of these knockout cell lines is the high efficiency and specificity of the gene editing process, which minimizes off-target effects typically seen in other knockout methodologies. Additionally, these cell lines are rigorously validated for consistent performance across multiple experiments, ensuring that researchers can rely on reproducible results.

Researchers and clinicians will find tremendous value in the LRRC58 Gene Knockout Cell Lines as they accelerate the understanding of gene function and pave the way for novel therapeutic strategies. Given the expertise of our company in genetic engineering and cell line development, we are devoted to providing high-quality biological products that enable cutting-edge research and innovation in the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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