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LRRC57 Knockout Cell Lines

Gene: LRRC57

Official Full Name: leucine rich repeat containing 57provided by HGNC

Gene Summary: Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21113 LRRC57 Knockout cell line (HeLa) Human LRRC57 1:3~1:6 Negative Online Inquiry
KO21114 LRRC57 Knockout cell line (HCT 116) Human LRRC57 1:2~1:4 Negative Online Inquiry
KO21115 LRRC57 Knockout cell line (HEK293) Human LRRC57 1:3~1:6 Negative Online Inquiry
KO21116 LRRC57 Knockout cell line (A549) Human LRRC57 1:3~1:4 Negative Online Inquiry

Background

LRRC57 Gene Knockout Cell Lines are a specialized biological product designed to facilitate the study of the LRRC57 gene's function by providing a cellular model where the gene has been intentionally disrupted. This knockout approach allows researchers to elucidate the role of LRRC57 in various biological processes, including signaling pathways, cellular differentiation, and disease mechanisms such as cancer and neurodegeneration.

The key mechanism behind these knockout cell lines is the use of CRISPR/Cas9 technology, a powerful tool for precise genome editing. By employing this method, scientists can create cell lines that lack the expression of the LRRC57 gene, providing a platform for in-depth functional assays. This enables researchers to observe the phenotypic consequences of LRRC57 deletion, assess its impact on cellular behavior, and identify potential genetic interactions and compensatory mechanisms.

The scientific importance of LRRC57 Gene Knockout Cell Lines extends beyond basic research; they have significant potential applications in drug discovery and therapeutic development. By analyzing how the loss of LRRC57 affects cellular responses, researchers can identify novel targets for pharmacological intervention and better understand disease phenotypes, which is critical for advancing personalized medicine.

Compared to traditional cell lines that express the LRRC57 gene, our knockout models offer distinct advantages, including the ability to study phenotype alterations in a controlled environment, without the confounding effects of gene expression. This specificity ensures more reliable data and reproducibility, which is crucial in both academic and commercial research environments.

For researchers and clinicians focused on genetic research, disease modeling, or therapy development, the LRRC57 Gene Knockout Cell Lines represent a valuable tool that enhances experimental rigor and the potential for groundbreaking discoveries. Our company possesses extensive expertise in genome editing technologies, ensuring that our products meet the highest standards of quality and reliability for users dedicated to advancing their scientific goals.

Please note that all services are for research use only. Not intended for any clinical use.

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