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LRRC45 Knockout Cell Lines

Gene: LRRC45

Official Full Name: leucine rich repeat containing 45provided by HGNC

Gene Summary: Located in several cellular components, including centrosome; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37512 LRRC45 Knockout cell line (HeLa) Human LRRC45 1:3~1:6 Negative Online Inquiry
KO37513 LRRC45 Knockout cell line (HCT 116) Human LRRC45 1:2~1:4 Negative Online Inquiry
KO37514 LRRC45 Knockout cell line (HEK293) Human LRRC45 1:3~1:6 Negative Online Inquiry
KO37515 LRRC45 Knockout cell line (A549) Human LRRC45 1:3~1:4 Negative Online Inquiry

Background

LRRC45 Gene Knockout Cell Lines are genetically modified cell lines featuring a targeted deletion of the LRRC45 gene, which encodes the leucine-rich repeat-containing protein 45. This gene plays a critical role in various cellular processes, including cell signaling, proliferation, and potentially, the regulation of immune responses. By establishing knockout models, researchers can explore the biological functions of LRRC45, providing insights into its involvement in disease mechanisms and cellular behaviors.

The key function of these cell lines lies in their utility for studying the effects of LRRC45 deficiency in various biological contexts. The knockout cells exhibit alterations in proliferation, differentiation, and response to environmental stimuli, allowing researchers to delineate the gene's role in cellular pathways and its contribution to diseases such as cancer or autoimmune disorders. Mechanistically, these cell lines are invaluable tools for functional genomics and can be utilized in high-throughput screening assays to identify compensatory pathways or therapeutic targets.

The scientific importance of LRRC45 Gene Knockout Cell Lines is underscored by their applications in both fundamental research and translational medicine. In research settings, they facilitate the elucidation of gene function and interaction networks. Clinically, understanding LRRC45's role may lead to novel therapeutic strategies aimed at modulating its pathway in disease states.

Compared to traditional methods, such as RNA interference or overexpression techniques, the knockout approach provides a more definitive assessment of gene function by producing a complete absence of the LRRC45 protein, thus eliminating off-target effects often associated with other methods. This specificity enhances the reliability of experimental results, making it a unique advantage for the end-user.

For researchers and clinicians alike, the LRRC45 Gene Knockout Cell Lines present a compelling opportunity to advance scientific knowledge and develop targeted therapies. They are designed to integrate seamlessly into various experimental workflows, providing a reliable means to investigate the functional implications of LRRC45 depletion.

Our company prides itself on a wealth of expertise in producing high-quality biological research tools. We are committed to empowering scientific discovery with innovative products like the LRRC45 Gene Knockout Cell Lines, which enable researchers to make significant advancements in understanding complex biological processes.

Please note that all services are for research use only. Not intended for any clinical use.

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