Home / LPAR6 Knockout Cell Lines

LPAR6 Knockout Cell Lines

Gene: LPAR6

Official Full Name: lysophosphatidic acid receptor 6provided by HGNC

Gene Summary: The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene aligns with an internal intron of the retinoblastoma susceptibility gene in the reverse orientation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07708 LPAR6 Knockout cell line (HEK293) Human LPAR6 1:3~1:6 Negative Online Inquiry
KO07709 LPAR6 Knockout cell line (A549) Human LPAR6 1:3~1:4 Negative Online Inquiry

Background

LPAR6 Gene Knockout Cell Lines are advanced cellular models specifically engineered to study the biological functions of the LPAR6 gene, a key player in the lysophosphatidic acid (LPA) signaling pathway. These cell lines exhibit complete knockout of the LPAR6 gene, enabling researchers to observe the resultant phenotypic and molecular effects associated with the absence of this receptor.

The primary function of the LPAR6 gene centers around its role in mediating LPA signaling, which influences a variety of physiological processes, including cellular proliferation, survival, migration, and differentiation. By using these knockout cell lines, researchers can dissect the intricacies of LPA-mediated pathways and their implications in various pathophysiological contexts such as cancer, fibrotic diseases, and neurodegenerative disorders. The knockout model allows for more straightforward investigations into the gene's specific molecular mechanisms, providing insights that are often muddied in wild-type systems where multiple signaling pathways can overlap.

In scientific research and clinical applications, LPAR6 Gene Knockout Cell Lines offer distinct advantages. They provide a more controlled environment to study gene function without the complexities introduced by endogenous gene expression. This specification allows for clearer conclusions regarding the role of LPAR6 in health and disease. Additionally, compared to traditional methods such as siRNA targeting or CRISPR/Cas9 edits in primary cells, the LPAR6 knockout cell lines are ready-to-use and eliminate variability associated with transfection efficiency or off-target effects.

For researchers and clinicians focused on elucidating the fundamentals of LPA signaling and its implications in disease mechanisms, these knockout cell lines represent an invaluable tool, simplifying experimental workflows and enhancing reproducibility. Furthermore, our company prides itself on its rigorous quality control and validation protocols, ensuring that each LPAR6 Gene Knockout Cell Line meets the highest standards of integrity and performance in scientific research. With our expertise in providing high-quality biological products, we are committed to facilitating groundbreaking discoveries and advancing the field of cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.