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LONRF2 Knockout Cell Lines

Gene: LONRF2

Official Full Name: LON peptidase N-terminal domain and ring finger 2provided by HGNC

Gene Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16509 LONRF2 Knockout cell line (HCT 116) Human LONRF2 1:2~1:4 Negative Online Inquiry
KO16510 LONRF2 Knockout cell line (HEK293) Human LONRF2 1:3~1:6 Negative Online Inquiry
KO16511 LONRF2 Knockout cell line (A549) Human LONRF2 1:3~1:4 Negative Online Inquiry

Background

LONRF2 Gene Knockout Cell Lines are engineered cellular models designed to facilitate the study of the LONRF2 gene's functions by creating a complete gene knockout. This innovative product employs CRISPR/Cas9 technology to specifically target and disrupt the LONRF2 gene, resulting in a precise deletion that allows researchers to investigate the gene's role in various cellular processes, including DNA repair, gene expression regulation, and cellular response to stress.

The mechanistic approach behind these knockout cell lines relies on the introduction of double-strand breaks at the LONRF2 locus, leading to non-homologous end joining (NHEJ) repair that renders the gene non-functional. By utilizing these cell lines, researchers can effectively assess the downstream effects of LONRF2 loss on cellular behavior, metabolic pathways, and overall cell viability. This is essential for understanding complex biological systems and disease mechanisms where LONRF2 may play a pivotal role.

The scientific importance of LONRF2 Gene Knockout Cell Lines extends to various research applications, including cancer biology, stem cell research, and pharmacogenomics, making them invaluable in the quest for targeted therapeutics. Their availability opens doors for novel investigations into the genetic underpinnings of diseases, enabling clinicians to identify potential biomarkers and therapeutic targets.

What sets these knockout cell lines apart from alternatives on the market is not only their specificity and precision but also their adaptability to a variety of experimental setups. Unlike traditional genetic manipulation methods that can result in off-target effects or incomplete knockouts, LONRF2 Gene Knockout Cell Lines provide a reliable and consistent tool for rigorous scientific inquiry.

By integrating these cell lines into research protocols, scientists and clinicians alike can uncover vital insights that could lead to breakthrough advancements in medical science. Furthermore, our company's commitment to innovation and high-quality products ensures that researchers receive reliable cell lines backed by comprehensive technical support and detailed product documentation, fostering successful experimental outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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