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LONRF1 Knockout Cell Lines

Gene: LONRF1

Official Full Name: LON peptidase N-terminal domain and ring finger 1provided by HGNC

Gene Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23395 LONRF1 Knockout cell line (HeLa) Human LONRF1 1:3~1:6 Negative Online Inquiry
KO23396 LONRF1 Knockout cell line (HCT 116) Human LONRF1 1:2~1:4 Negative Online Inquiry
KO23397 LONRF1 Knockout cell line (HEK293) Human LONRF1 1:3~1:6 Negative Online Inquiry
KO23398 LONRF1 Knockout cell line (A549) Human LONRF1 1:3~1:4 Negative Online Inquiry

Background

LONRF1 Gene Knockout Cell Lines are genetically modified cell lines that have undergone targeted gene knockout of the LONRF1 gene, which encodes for the Lon peptidase-like domain protein involved in various cellular functions, including mitochondrial quality control and stress response. These cell lines serve as a powerful tool for researchers aiming to investigate the biological roles of LONRF1 in cellular processes and disease states, particularly in the context of cancer, neurodegenerative disorders, and metabolic diseases.

The mechanism underlying the function of LONRF1 Gene Knockout Cell Lines relies on the precise alteration of the cellular genome through CRISPR-Cas9 technology or other gene-editing methods, enabling researchers to elucidate the role of the LONRF1 gene by observing the resulting phenotypic changes. By knocking out LONRF1, these cell lines allow for the examination of pathways that may be impacted by its absence, as well as the potential compensatory mechanisms employed by the cell.

The scientific importance of these cell lines is profound, as they provide valuable insights into gene function and regulation, making them indispensable for basic research and translational studies. In clinical settings, understanding LONRF1's contribution to disease processes could lead to novel therapeutic strategies, targeting specific pathways influenced by this gene.

In comparison to alternative products, LONRF1 Gene Knockout Cell Lines offer a high degree of specificity and reliability, reducing off-target effects that may complicate research outcomes. Furthermore, the ability to use these cell lines in various model organisms ensures that findings are more translatable to physiological conditions.

Researchers and clinicians will find great value in LONRF1 Gene Knockout Cell Lines due to their potential to advance knowledge in molecular biology, genetics, and disease mechanisms. These cell lines are particularly suited for drug development studies and the identification of biomarkers for diagnostic purposes.

At our company, we are committed to providing high-quality genetic tools backed by extensive expertise in molecular genetics and cell biology, enabling transformative research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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