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LNX1 Knockout Cell Lines

Gene: LNX1

Official Full Name: ligand of numb-protein X 1provided by HGNC

Gene Summary: This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24693 LNX1 Knockout cell line (HeLa) Human LNX1 1:3~1:6 Negative Online Inquiry
KO24694 LNX1 Knockout cell line (HCT 116) Human LNX1 1:2~1:4 Negative Online Inquiry
KO24695 LNX1 Knockout cell line (HEK293) Human LNX1 1:3~1:6 Negative Online Inquiry

Background

LNX1 Gene Knockout Cell Lines are innovative biological tools engineered specifically to eliminate the expression of the LNX1 gene in various cell types. These cell lines serve as critical research models for studying the functional consequences of LNX1 deficiency, offering insights into its roles in cellular processes, including signal transduction, differentiation, and response to environmental stimuli.

The LNX1 knockout mechanism operates through CRISPR-Cas9 technology, which enables precise editing of the genome. This cutting-edge approach allows researchers to create reliable, reproducible models that accurately reflect the loss of LNX1, facilitating the investigation of its biological implications in various contexts, such as neurodegeneration, cellular growth regulation, and disease pathology.

From a scientific perspective, LNX1 Gene Knockout Cell Lines are invaluable in both basic and applied research settings. Their utility extends to understanding the molecular pathways involved in various diseases, thereby aiding the development of targeted therapeutic strategies. Furthermore, these cell lines can provide a foundation for drug testing and discovery, making them pertinent for translational research.

What sets LNX1 Gene Knockout Cell Lines apart from traditional gene silencing methods—such as RNA interference—is their permanence and stability. Once the LNX1 gene is disrupted, the knockout state is maintained in subsequent cell divisions, allowing for long-term studies that are not feasible with transient knockdown approaches. This stability enhances the reproducibility of experimental results, making these cell lines a more dependable choice for researchers.

For researchers, clinicians, or biotechnology professionals, the adoption of LNX1 Gene Knockout Cell Lines represents a critical step toward unraveling the complex role of the LNX1 gene and its impacts on human health. In a marketplace replete with genetic manipulation tools, these knockout lines distinguish themselves through their robustness and applicability, proving their worth in advancing genetic studies.

With a commitment to innovation and excellence, our company specializes in developing state-of-the-art biological products, including LNX1 Gene Knockout Cell Lines, backed by a team of experts dedicated to supporting the scientific community in their quest for knowledge and breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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