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LMTK2 Knockout Cell Lines

Gene: LMTK2

Official Full Name: lemur tyrosine kinase 2provided by HGNC

Gene Summary: The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. [provided by RefSeq, Oct 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02386 LMTK2 Knockout cell line (HeLa) Human LMTK2 1:3~1:6 Negative Online Inquiry
KO02387 LMTK2 Knockout cell line (HCT 116) Human LMTK2 1:2~1:4 Negative Online Inquiry
KO02388 LMTK2 Knockout cell line (HEK293) Human LMTK2 1:3~1:6 Negative Online Inquiry
KO02389 LMTK2 Knockout cell line (A549) Human LMTK2 1:3~1:4 Negative Online Inquiry

Background

LMTK2 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the LMTK2 gene, a mediator implicated in various cellular processes, including cell signaling, proliferation, and differentiation. By creating knockout versions of this gene, these cell lines enable researchers to elucidate its functional roles and understand the biological pathways influenced by LMTK2 in health and disease.

The key function of LMTK2 Gene Knockout Cell Lines lies in their ability to provide a platform for loss-of-function studies, allowing scientists to observe the phenotypic and molecular consequences of LMTK2 deficiency. This mechanism aids in examining alterations in cellular behavior, signaling cascades, and gene expression patterns that would not be observable in wild-type cells. The knockout approach is particularly valuable for functional genomics, drug screening, and the investigation of potential therapeutic targets in cancer and neurodegenerative diseases.

The scientific importance of these cell lines is underscored by their applications in both research and clinical settings. They support the development of targeted therapies by shedding light on LMTK2’s role in disease mechanisms, facilitating biomarker identification, and providing preclinical models for drug testing. Moreover, their contribution to the growing field of personalized medicine aligns with the increasing need for bespoke therapeutic strategies tailored to individual genetic profiles.

In comparison to alternative research models, LMTK2 Gene Knockout Cell Lines stand out due to their specificity and relevance to human physiology. Unlike conventional models that may not accurately mimic human cellular contexts, these lines offer enhanced translational potential. Additionally, they are designed for ease of use, ensuring time-efficient experimental setups without compromising data integrity.

Researchers and clinicians looking to uncover the intricate workings of cellular mechanisms related to LMTK2 will find substantial value in these knockout cell lines. They not only provide critical insights into fundamental biology but also open avenues for innovative therapeutic discoveries.

Our company brings deep expertise in the field of recombinant DNA technology and cellular engineering, ensuring the highest quality products that support scientific advancements and empower researchers in their quest to address complex biological questions.

Please note that all services are for research use only. Not intended for any clinical use.

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