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LMOD1 Knockout Cell Lines

Gene: LMOD1

Official Full Name: leiomodin 1provided by HGNC

Gene Summary: The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01769 LMOD1 Knockout cell line (HEK293) Human LMOD1 1:3~1:6 Negative Online Inquiry

Background

LMOD1 Gene Knockout Cell Lines are precisely engineered cellular models in which the LMOD1 gene, critical for cytoskeletal dynamics and muscle development, has been functionally disrupted. By utilizing advanced CRISPR-Cas9 technology, these cell lines enable researchers to study the biochemical pathways influenced by LMOD1, investigate its role in cellular processes, and understand its implications in various diseases, particularly those affecting muscle function or heart health.

The primary function of LMOD1 is to regulate the actin cytoskeleton, facilitating proper sarcomere assembly and muscle contraction. By creating knockout variants, scientists can elucidate the mechanistic effects of LMOD1 deficiency on muscle cells, contributing to our understanding of muscular dystrophies, cardiomyopathies, and other myopathies. This research aids in deciphering the complex interactions and pathways that may leverage new therapeutic targets or assist in advancing personalized medicine approaches.

The scientific importance of LMOD1 Gene Knockout Cell Lines is underscored by their applicability in both basic biological research and preclinical drug development. These cell lines provide an invaluable tool for phenotyping, drug screening, and validating therapeutic strategies aimed at correcting gene defects. Compared to conventional models—such as wild-type cell lines or animal models—knockout cell lines offer precise genetic modification with fewer biological variabilities, leading to more reproducible and reliable results.

Furthermore, the LMOD1 Gene Knockout Cell Lines present significant advantages over alternative models, including ease of manipulation, scalability, and the ability to study human-specific gene functions in an in vitro environment. Researchers, clinicians, and pharmaceutical companies engaged in muscle and cardiac research can leverage these cell lines to advance their work with confidence, knowing they are utilizing a cutting-edge tool.

Our company, with extensive expertise in genetic engineering and cell line development, is committed to providing high-quality biological products that empower researchers to push the boundaries of scientific knowledge. By selecting our LMOD1 Gene Knockout Cell Lines, you invest in a reliable and valuable resource designed to foster impactful discoveries in muscle biology and beyond.

Please note that all services are for research use only. Not intended for any clinical use.

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