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LMF2 Knockout Cell Lines

Gene: LMF2

Official Full Name: lipase maturation factor 2provided by HGNC

Gene Summary: Predicted to be involved in protein maturation. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07015 LMF2 Knockout cell line (HeLa) Human LMF2 1:3~1:6 Negative Online Inquiry
KO07016 LMF2 Knockout cell line (HCT 116) Human LMF2 1:2~1:4 Negative Online Inquiry
KO07017 LMF2 Knockout cell line (HEK293) Human LMF2 1:3~1:6 Negative Online Inquiry
KO07018 LMF2 Knockout cell line (A549) Human LMF2 1:3~1:4 Negative Online Inquiry

Background

LMF2 Gene Knockout Cell Lines are specialized genetically modified cell lines engineered to lack the expression of the LMF2 gene, playing a pivotal role in lipid metabolism and related signaling pathways. These unique cell lines utilize CRISPR-Cas9 technology to achieve precise gene knockout, enabling researchers to investigate the functional contributions of LMF2 in various biological contexts. The absence of LMF2 allows for in-depth studies into its role in lipid droplet biogenesis, cellular energy homeostasis, and metabolic disorders, thereby providing an invaluable platform for experimental analysis.

The key functions of LMF2 Gene Knockout Cell Lines lie in their ability to unveil the downstream effects of LMF2 deficiency on cellular lipids and overall metabolic health. These cell lines respond to external stimuli differently compared to wild-type counterparts, allowing for observation of altered lipid profiles and associated signaling cascades that can lead to insights into pathophysiological conditions such as obesity, diabetes, and cardiovascular diseases.

Scientifically, these cell lines serve as crucial tools in both basic and applied research settings, providing a foundation for drug discovery and therapeutic interventions targeting metabolic pathways. The ability to perform targeted assays on knockout cells significantly enhances the reproducibility of results and enables researchers to pinpoint specific gene functions without the confounding effects found in partial knockdown or overexpression models.

In comparison to alternative models, such as traditional knockdown techniques or embryo-derived knockout models, LMF2 Gene Knockout Cell Lines offer superior precision and a more straightforward verification process. They also enable rapid generation of insights with less genetic variability, facilitating quicker transition from discovery to application.

For researchers and clinicians focused on lipid metabolism and related illnesses, these cell lines are exceptionally valuable. Their ability to elucidate the consequences of LMF2 loss-of-function provides critical knowledge that can inform therapeutic strategies, potentially leading to the development of targeted treatments.

Our company possesses extensive expertise in genetic engineering and cellular biology, providing high-quality gene knockout models that empower scientific advancements. With our commitment to innovation and reliability, we strive to support researchers in overcoming the challenges posed by complex biological questions in the field of lipid metabolism.

Please note that all services are for research use only. Not intended for any clinical use.

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