Gene: LMAN1L
Official Full Name: lectin, mannose binding 1 likeprovided by HGNC
Gene Summary: This gene encodes a mannose-binding type 1 transmembrane protein that contains an N-terminal lectin-like carbohydrate recognition domain. The encoded protein is similar in structure to lectins found in leguminous plants. This lectin is thought to transport newly synthesized glycoproteins from the endoplasmic reticulum (ER) to the ER-Golgi intermediate compartment. [provided by RefSeq, Jan 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21959 | LMAN1L Knockout cell line (HEK293) | Human | LMAN1L | 1:3~1:6 | Negative | Online Inquiry |
LMAN1L Gene Knockout Cell Lines are a crucial biotechnological tool featuring genetically modified cell lines in which the LMAN1L gene has been systematically disrupted. The LMAN1L (lectin mannose-binding 1-like) gene, known for its role in glycoprotein trafficking, is critical for maintaining cellular homeostasis and normal physiological functions. By utilizing advanced CRISPR/Cas9 technology, these knockout cell lines effectively model the absence of LMAN1L, allowing researchers to investigate its functional roles in various biological processes, including protein transport, glycosylation, and cellular responses to stress.
The primary mechanism that underpins these cell lines involves gene editing to create a targeted knockout of the LMAN1L gene, leading to a precise assessment of downstream effects on cellular physiology. Researchers can analyze how the loss of LMAN1L affects glycoprotein metabolism and related pathways, which is essential for understanding conditions like congenital disorders of glycosylation and certain cancer types.
Scientifically, LMAN1L Gene Knockout Cell Lines provide invaluable insights into fundamental biological processes, making them an essential resource in both research and clinical settings. Their application ranges from drug discovery and developing therapeutic strategies to elucidating the molecular underpinnings of diseases involving glycosylation abnormalities.
What sets our LMAN1L Gene Knockout Cell Lines apart from alternatives is their high specificity and reliability. Our extensive validation ensures that these cell lines exhibit consistent knockout efficiency and functionality, thereby enhancing experimental reproducibility. Moreover, they are available with comprehensive support and detailed characterization data, giving researchers confidence in their experimental design.
Choosing LMAN1L Gene Knockout Cell Lines empowers researchers and clinicians to advance their work with a robust model system tailored for in-depth investigations of LMAN1L-related pathways. Our company, recognized for its dedication to excellence in genetic engineering and cell line development, stands behind these products with extensive expertise and a commitment to providing high-quality biological tools for the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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