Gene: LIN7A
Official Full Name: lin-7 homolog A, crumbs cell polarity complex componentprovided by HGNC
Gene Summary: The protein encoded by this gene is involved in generating and maintaining the asymmetric distribution of channels and receptors at the cell membrane. The encoded protein also is required for the localization of some specific channels and can be part of a protein complex that couples synaptic vesicle exocytosis to cell adhesion in the brain. [provided by RefSeq, May 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33814 | LIN7A Knockout cell line (HCT 116) | Human | LIN7A | 1:2~1:4 | Negative | Online Inquiry |
KO33815 | LIN7A Knockout cell line (HEK293) | Human | LIN7A | 1:3~1:6 | Negative | Online Inquiry |
KO33816 | LIN7A Knockout cell line (A549) | Human | LIN7A | 1:3~1:4 | Negative | Online Inquiry |
LIN7A Gene Knockout Cell Lines are precisely engineered cellular models in which the LIN7A gene has been inactivated to study its role in cellular physiology and relevant disease states. The LIN7A protein is part of the lin-7 family of proteins that play pivotal roles in the assembly of protein complexes at the cell membrane, influencing processes such as signaling pathways and cellular adhesion. By utilizing CRISPR-Cas9 technology to create these knockout cell lines, researchers can closely examine the effects of LIN7A gene disruption on various cellular functions, including synaptic transmission and cell polarization.
The significance of LIN7A Gene Knockout Cell Lines in research and clinical applications is profound. These cell lines enable scientists to dissect the molecular mechanisms underlying neurological disorders and cancers, where LIN7A dysregulation may contribute to pathophysiology. Furthermore, they provide a robust platform for drug discovery and therapeutic interventions, allowing for the screening of candidates aimed at restoring normal function or mitigating adverse effects resulting from LIN7A deficiency.
One of the key advantages of utilizing our LIN7A Gene Knockout Cell Lines is their high reproducibility and consistency, attributes that are crucial in experimental settings. Unlike traditional methods of gene knockout that may present variability and time-consuming protocols, our system ensures a streamlined approach that minimizes experimental noise and enhances data integrity. This reliability positions our product as an indispensable tool for researchers seeking to yield definitive conclusions in their studies.
By choosing our LIN7A Gene Knockout Cell Lines, researchers and clinicians gain access to a valuable resource that accelerates the understanding of gene function and disease pathology. This product exemplifies our company's commitment to advancing biological research through innovative and scientifically advanced solutions. With a dedicated team of molecular biologists and a commitment to quality, we continuously aim to deliver cutting-edge products tailored to meet the needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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