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LIMD2 Knockout Cell Lines

Gene: LIMD2

Official Full Name: LIM domain containing 2provided by HGNC

Gene Summary: Predicted to enable actin filament binding activity. Predicted to be involved in actin filament bundle assembly. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25912 LIMD2 Knockout cell line (HeLa) Human LIMD2 1:3~1:6 Negative Online Inquiry
KO25913 LIMD2 Knockout cell line (HCT 116) Human LIMD2 1:2~1:4 Negative Online Inquiry
KO25914 LIMD2 Knockout cell line (HEK293) Human LIMD2 1:3~1:6 Negative Online Inquiry
KO25915 LIMD2 Knockout cell line (A549) Human LIMD2 1:3~1:4 Negative Online Inquiry

Background

LIMD2 Gene Knockout Cell Lines are genetically engineered cell lines wherein the LIM domain-containing protein 2 (LIMD2) gene has been selectively disrupted. This innovative product enables researchers to investigate the biological functions associated with LIMD2, a protein implicated in various cellular processes, including signal transduction, cytoskeletal organization, and cell proliferation. By utilizing these knockout cell lines, scientists can elucidate the specific roles of LIMD2 in cellular mechanisms, disease pathogenesis, and therapeutic responses.

The key function of the LIMD2 gene knockout lies in its ability to facilitate the study of gene function through loss-of-function analysis. By disrupting the LIMD2 gene, these cell lines provide a valuable model for examining how the absence of this protein influences cellular behavior and interactions. Researchers can manipulate the cells under various experimental conditions, including drug treatments or stress responses, allowing for insights into pathways that are altered due to LIMD2 absence.

Scientifically, LIMD2 has garnered attention for its involvement in cancer metastasis and immune response regulation. Thus, these knockout cell lines are particularly valuable in both fundamental research and clinical applications, offering a platform for drug discovery and the development of targeted therapies. Their relevance extends to studies focusing on how the modulation of LIMD2 can impact tumor growth and immune cell dynamics, making them indispensable tools in oncology and immunology.

Compared to alternative methods, such as RNA interference or transgenic models, LIMD2 Gene Knockout Cell Lines present distinct advantages, including a complete and permanent loss of gene function that is crucial for rigorous and reproducible experimental outcomes. They also enable researchers to bypass potential off-target effects commonly associated with knockdown strategies, thus ensuring more reliable data.

For researchers and clinicians engaging in the quest to unravel complex biological questions or develop novel therapies, these cell lines represent cutting-edge resources that streamline experimentation while enhancing the accuracy of results. Our company prides itself on its commitment to advancing scientific research through high-quality, meticulously developed biological products. With extensive expertise in genetic engineering and cell line development, we stand as a trusted partner in your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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