Gene: LIMCH1
Official Full Name: LIM and calponin homology domains 1provided by HGNC
Gene Summary: Enables myosin II head/neck binding activity. Involved in several processes, including cytoplasmic actin-based contraction involved in cell motility; positive regulation of stress fiber assembly; and regulation of focal adhesion assembly. Located in myosin II complex and stress fiber. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05746 | LIMCH1 Knockout cell line (HeLa) | Human | LIMCH1 | 1:3~1:6 | Negative | Online Inquiry |
KO05747 | LIMCH1 Knockout cell line (HCT 116) | Human | LIMCH1 | 1:2~1:4 | Negative | Online Inquiry |
KO05748 | LIMCH1 Knockout cell line (HEK293) | Human | LIMCH1 | 1:3~1:6 | Negative | Online Inquiry |
KO05749 | LIMCH1 Knockout cell line (A549) | Human | LIMCH1 | 1:3~1:4 | Negative | Online Inquiry |
LIMCH1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the LIMCH1 gene, which encodes a protein integral to various biological processes, including cytoskeletal dynamics and cellular signaling pathways. This product allows researchers to study the specific functional role of LIMCH1 in cellular behavior, enabling a deeper understanding of its involvement in essential physiological processes and diseases.
The primary function of these cell lines is to facilitate the investigation of cellular mechanisms that depend on the LIMCH1 gene. By disrupting the LIMCH1 gene, researchers can observe changes in cellular morphology, migration patterns, and signaling cascades, which can shed light on the gene's contributions to conditions such as cancer and neurodegeneration. Furthermore, this product enables high-throughput screening applications, gene therapy development, and drug discovery, using a controlled environment to assess phenotypic changes in response to targeted interventions.
The scientific importance of LIMCH1 Gene Knockout Cell Lines lies in their ability to model disease states accurately, providing key insights that advance both basic research and therapeutic development. Given their specific genetic modification, these cell lines offer a unique opportunity for researchers to dissect the roles of LIMCH1 in cellular contexts that traditional models cannot provide.
Compared to alternative cell line models, the advantages of using LIMCH1 Gene Knockout Cell Lines include their straightforward genetic modification, reproducibility, and the ability to be used in various experimental setups, making them versatile tools for researchers. Additionally, the availability of these knockout models accelerates the timeline for discovery and validation of therapeutic targets.
In summary, LIMCH1 Gene Knockout Cell Lines represent an invaluable resource for scientific inquiry, equipping researchers and clinicians with the precise tools needed to study the complex roles of LIMCH1. Our company prides itself on delivering high-quality biological products backed by extensive research and expertise, ensuring that our customers have access to reliable and innovative solutions for their scientific endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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