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LGALS2 Knockout Cell Lines

Gene: LGALS2

Official Full Name: galectin 2provided by HGNC

Gene Summary: The protein encoded by this gene is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and can bind to lymphotoxin-alpha. A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant increased risk of myocardial infarction. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36845 LGALS2 Knockout cell line (HEK293) Human LGALS2 1:3~1:6 Negative Online Inquiry

Background

LGALS2 Gene Knockout Cell Lines are genetically engineered cell lines in which the GAL-3 (Lectin, Galactoside-Binding, Soluble, 2) gene has been disrupted, allowing researchers to investigate the role of this protein in various biological processes. LGALS2 is essential for modulating immune responses and has been implicated in cancer progression, inflammation, and fibrosis. By using these knockout cell lines, scientists can delve into the specific functions of LGALS2, elucidating its impact on cell signaling pathways, immune cell interactions, and the tumor microenvironment.

These cell lines operate through the absence of the LGALS2 gene product, which affords a unique opportunity to observe resultant phenotypic changes in cellular behavior. Researchers can assess alterations in proliferation, migration, and apoptosis, providing insights into advanced therapeutic targets. This complete knockout allows for precise mechanistic studies that are often masked in wild-type lines with functional redundancy, providing clear data on the gene's influence in disease contexts.

In research and clinical settings, LGALS2 Gene Knockout Cell Lines are invaluable for drug discovery and biomarker identification. The responsiveness of these cells to various pharmacological agents, alongside their use in high-throughput screening assays, enables the development of targeted therapies that specifically hinder the pathways influenced by LGALS2.

The distinct advantages of these cell lines include the rigor of genetic manipulation and their specificity to LGALS2, which sets them apart from conventional models. Unlike alternative cell lines that may produce artefactual results due to functional redundancy or compensatory pathways, these knockout lines allow for a more accurate representation of the role of LGALS2 in disease mechanisms.

Researchers, clinicians, and pharmaceutical developers will find these cell lines particularly valuable, as they provide robust tools to translate basic science into clinical innovations, fostering advancements in treatment strategies aimed at conditions influenced by the galectin family.

At [Your Company Name], we specialize in providing high-quality biological products tailored for cutting-edge research. Our expertise ensures that our LGALS2 Gene Knockout Cell Lines are rigorously validated and characterized, empowering scientists to push the boundaries of biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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