Gene: LDB1
Official Full Name: LIM domain binding 1provided by HGNC
Gene Summary: Enables LIM domain binding activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and enzyme binding activity. Involved in negative regulation of DNA-templated transcription and positive regulation of transcription by RNA polymerase II. Located in chromatin. Part of beta-catenin-TCF complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04836 | LDB1 Knockout cell line (HeLa) | Human | LDB1 | 1:3~1:6 | Negative | Online Inquiry |
KO04837 | LDB1 Knockout cell line (HCT 116) | Human | LDB1 | 1:2~1:4 | Negative | Online Inquiry |
KO04838 | LDB1 Knockout cell line (HEK293) | Human | LDB1 | 1:3~1:6 | Negative | Online Inquiry |
KO04839 | LDB1 Knockout cell line (A549) | Human | LDB1 | 1:3~1:4 | Negative | Online Inquiry |
LDB1 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the LDB1 gene, a critical component involved in various cellular processes, including gene regulation and development. These knockout cell lines facilitate the in-depth study of the LDB1 gene's functions, its role in transcriptional regulation, and its implications in developmental biology and disease mechanisms.
The primary mechanism of these cell lines involves the targeted deletion of the LDB1 gene using cutting-edge technologies such as CRISPR/Cas9 or RNA interference. By eliminating LDB1, researchers can observe the resulting phenotypic changes and alterations in cellular signaling pathways. This provides invaluable insights into how the absence of this gene influences cellular differentiation, developmental pathways, and contributions to conditions such as cancer or congenital disorders.
The scientific significance of LDB1 Gene Knockout Cell Lines lies in their potential applications in fundamental research and translational medicine. These cell lines can serve as powerful tools for drug discovery, allowing scientists to screen for compounds that may restore normal function in systems affected by LDB1 deficiency. In clinical settings, understanding the role of LDB1 could lead to the development of gene therapies or genetic interventions in relevant disorders.
Compared to other gene knockout systems, our LDB1 Gene Knockout Cell Lines are validated for robustness, reproducibility, and ease of use, providing researchers with a reliable model for their investigations. The unique selling point is the comprehensive characterization provided with each cell line, ensuring that users have the confidence in the data they generate.
For researchers and clinicians, investing in LDB1 Gene Knockout Cell Lines can accelerate the progress of your studies, enhancing the potential for significant scientific breakthroughs. Our company specializes in high-quality biological products backed by rigorous research and development, ensuring that our customers receive exceptional tools to advance their research efforts effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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