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LCA5L Knockout Cell Lines

Gene: LCA5L

Official Full Name: lebercilin LCA5 likeprovided by HGNC

Gene Summary: Predicted to be involved in intraciliary transport. Predicted to be active in axoneme. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22124 LCA5L Knockout cell line (HeLa) Human LCA5L 1:3~1:6 Negative Online Inquiry
KO22125 LCA5L Knockout cell line (HCT 116) Human LCA5L 1:2~1:4 Negative Online Inquiry
KO22126 LCA5L Knockout cell line (HEK293) Human LCA5L 1:3~1:6 Negative Online Inquiry
KO22127 LCA5L Knockout cell line (A549) Human LCA5L 1:3~1:4 Negative Online Inquiry

Background

LCA5L Gene Knockout Cell Lines are specialized, genetically modified cell lines that have been engineered to lack the functional LCA5L gene. This product plays a crucial role in facilitating research in gene function, disease mechanisms, and potential therapeutic targets related to disorders associated with LCA5L deficiency, such as certain forms of retinal degeneration. By providing a controlled environment devoid of the LCA5L gene, these knockout cell lines allow researchers to dissect the biological pathways influenced by this gene, elucidating its specific contributions to cellular functions and disease pathology.

The primary mechanism of action lies in the targeted disruption of the LCA5L gene, achieved through advanced techniques such as CRISPR/Cas9 or RNA interference. Researchers can utilize these engineered cells to observe the resultant phenotypic changes, enabling a deeper understanding of gene expression patterns and the resultant cellular responses under various experimental conditions. This is invaluable for elucidating cellular dysfunctions that may arise in disease states, particularly in retinal tissues where LCA5L plays a pivotal role.

In terms of scientific importance, LCA5L Gene Knockout Cell Lines serve as robust models for studying genetic diseases in vitro, quintessential for developing new treatments and therapeutic strategies. The versatility of these cell lines allows for usage in drug screening, gene editing validation, and the modeling of gene therapies, making them indispensable tools in both academic and clinical research settings.

What sets our LCA5L Gene Knockout Cell Lines apart from other genetic models is their unparalleled reliability and reproducibility, which ensures consistent results across experiments. These cell lines are developed under stringent quality control measures, providing researchers with confidence in their experimental outcomes. Furthermore, extensive characterization data accompanies our product, ensuring users have a complete understanding of the cell lines’ behavior and applications, which enhances research accuracy.

For researchers and clinicians focused on gene therapy, regenerative medicine, or understanding retinal diseases, our LCA5L Gene Knockout Cell Lines provide significant value by offering a precise and efficient method to investigate complex biological questions. With our commitment to scientific advancement and expertise in genetic engineering, we strive to provide top-tier biological tools that empower the scientific community in their quest for innovative solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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