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LBX2 Knockout Cell Lines

Gene: LBX2

Official Full Name: ladybird homeobox 2provided by HGNC

Gene Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in several processes, including positive regulation of convergent extension involved in gastrulation; positive regulation of non-canonical Wnt signaling pathway; and regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24179 LBX2 Knockout cell line (HCT 116) Human LBX2 1:2~1:4 Negative Online Inquiry
KO24180 LBX2 Knockout cell line (HEK293) Human LBX2 1:3~1:6 Negative Online Inquiry
KO24181 LBX2 Knockout cell line (A549) Human LBX2 1:3~1:4 Negative Online Inquiry

Background

The LBX2 Gene Knockout Cell Lines are precisely engineered cellular models designed to study the biological functions of the LBX2 gene, which is crucial for the regulation of various developmental processes and neural functions. By utilizing CRISPR-Cas9 technology, these cell lines provide a powerful tool for elucidating the role of LBX2 in cellular pathways, enabling researchers to investigate its implications in neurodevelopmental disorders, muscle differentiation, and cancer biology.

Key functions of the LBX2 Gene Knockout Cell Lines involve the ablation of LBX2 expression, which allows for the assessment of downstream effects on gene expression and cellular behavior. By examining how these cell lines respond to various stimuli and treatments compared to their wild-type counterparts, researchers can identify critical gene interactions and mechanisms that may influence development and disease progression.

The scientific importance of these cell lines is underscored by their broad applications in both academic research and clinical settings. They serve as valuable models for investigating the etiology of neurodevelopmental disorders, thereby contributing to the development of potential therapeutic interventions. Additionally, the LBX2 gene has been implicated in several malignancies, making these cell lines particularly relevant for cancer research, where they can be used to screen for novel drugs and elucidate tumorigenesis mechanisms.

What sets LBX2 Gene Knockout Cell Lines apart from other genetic models is their precise genome editing, which significantly increases reliability and reproducibility in experimental outcomes. Unlike traditional knockout models, which may exhibit off-target effects or incomplete gene ablation, these cell lines ensure definitive elimination of the LBX2 gene, providing unambiguous results.

For researchers and clinicians focused on neurobiology, gene regulation, and therapeutic development, the LBX2 Gene Knockout Cell Lines present an indispensable resource. Access to this product empowers users with advanced tools to explore the complex functions of LBX2, making significant strides in their research.

Our company specializes in the development of innovative biological tools, combining cutting-edge technology with deep expertise to provide researchers with reliable solutions for their scientific inquiries. By choosing our LBX2 Gene Knockout Cell Lines, you are equipping your research with precise, dependable models that enhance the potential for discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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