Gene: LANCL1
Official Full Name: LanC like glutathione S-transferase 1provided by HGNC
Gene Summary: This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31980 | LANCL1 Knockout cell line (HeLa) | Human | LANCL1 | 1:3~1:6 | Negative | Online Inquiry |
KO31981 | LANCL1 Knockout cell line (HCT 116) | Human | LANCL1 | 1:2~1:4 | Negative | Online Inquiry |
KO31982 | LANCL1 Knockout cell line (HEK293) | Human | LANCL1 | 1:3~1:6 | Negative | Online Inquiry |
KO31983 | LANCL1 Knockout cell line (A549) | Human | LANCL1 | 1:3~1:4 | Negative | Online Inquiry |
LANCL1 Gene Knockout Cell Lines are genetically engineered cell lines in which the LANCL1 gene has been specifically disrupted using precise genome-editing techniques, such as CRISPR/Cas9. The LANCL1 gene encodes for the LANCL1 protein, which plays a significant role in various cellular processes, including the regulation of immune responses, metabolism, and cellular signaling pathways. By creating knockout models, researchers can thoroughly investigate the function of this gene and its protein product in various biological contexts.
The primary mechanism of these cell lines involves the deletion of the LANCL1 gene, leading to a loss of expression of its associated protein. This allows researchers to study the phenotypic consequences of LANCL1 absence, assess its influence on cell proliferation, apoptosis, signaling pathways, and response to pharmacological agents. Such information is critical in elucidating the molecular mechanisms underlying diseases where LANCL1 is implicated, thereby contributing to a better understanding of both normal physiology and pathology.
The scientific importance of LANCL1 Gene Knockout Cell Lines lies in their capability to serve as a model for researching conditions such as autoimmune diseases, metabolic disorders, and cancer. In clinical settings, these models can provide insights into therapeutic targets and the development of novel treatment strategies. Moreover, they enable high-throughput screening of potential drug candidates that may interact with the LANCL1 pathway.
One of the unique selling points of our LANCL1 Gene Knockout Cell Lines is their high specificity and reproducibility, which sets them apart from traditional methods that may produce heterogeneous populations with inconsistent knockout efficiency. Additionally, our lines are validated for use in various applications, ensuring reliability in experimental designs. Researchers and clinicians benefit from these streamlined models as they facilitate the generation of robust data while reducing time and resource expenditure in their projects.
Our company's dedication to advancing genetic research and providing innovative biological tools is reflected in our LANCL1 Gene Knockout Cell Lines. With expertise in genetic engineering and a commitment to quality, we offer products that empower scientists to conduct groundbreaking research and contribute to advancements in molecular biology and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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