Gene: LAMP3
Official Full Name: lysosomal associated membrane protein 3provided by HGNC
Gene Summary: Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27865 | LAMP3 Knockout cell line (HeLa) | Human | LAMP3 | 1:3~1:6 | Negative | Online Inquiry |
KO27866 | LAMP3 Knockout cell line (HCT 116) | Human | LAMP3 | 1:2~1:4 | Negative | Online Inquiry |
KO27867 | LAMP3 Knockout cell line (HEK293) | Human | LAMP3 | 1:3~1:6 | Negative | Online Inquiry |
LAMP3 Gene Knockout Cell Lines are specialized cellular models in which the LAMP3 gene, associated with lysosomal biogenesis and immune responses, has been precisely inactivated through gene editing techniques. These cell lines provide researchers a vital tool to investigate the functional role of LAMP3 in various biological processes, including lysosomal function, immune evasion by pathogens, and potential involvement in disease states such as cancer.
Key functions of LAMP3 Gene Knockout Cell Lines revolve around their ability to mimic pathological conditions where LAMP3 is upregulated or downregulated. By studying these cells, researchers can elucidate the mechanisms by which LAMP3 influences lysosomal dynamics and cellular signaling pathways critical for survival, proliferation, and immune responses. The knockout models allow for the examination of cellular behavior in the absence of the LAMP3 protein, thereby facilitating studies on its role in autophagy, apoptosis, and responses to intracellular infections.
In the scientific arena, these LAMP3 knockout cell lines are invaluable in both basic and applied research settings. They can be employed to screen potential therapeutic agents, assess the impact of the LAMP3 gene on drug resistance, and ultimately contribute to the development of targeted treatment strategies for diseases characterized by dysregulated lysosomal function. Compared to conventional cell lines, the LAMP3 knockout variants offer enhanced specificity and relevance, allowing researchers to generate more reliable data regarding treatment efficacy and mechanistic insights.
The value of LAMP3 Gene Knockout Cell Lines lies in their potential to accelerate discoveries in fields such as immunology, oncology, and genetics. By utilizing these models, researchers can gain deeper insights into the significance of lysosomal function in health and disease, paving the way for innovative therapies and clinical applications. Our company, with its extensive expertise in genetic engineering and cell line development, provides high-quality, ready-to-use LAMP3 knockout cell lines, empowering scientists to advance their research with confidence and precision.
Please note that all services are for research use only. Not intended for any clinical use.
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