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KRTAP23-1 Knockout Cell Lines

Gene: KRTAP23-1

Official Full Name: keratin associated protein 23-1provided by HGNC

Gene Summary: Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20425 KRTAP23-1 Knockout cell line (HeLa) Human KRTAP23-1 1:3~1:6 Negative Online Inquiry
KO20426 KRTAP23-1 Knockout cell line (HCT 116) Human KRTAP23-1 1:2~1:4 Negative Online Inquiry
KO20427 KRTAP23-1 Knockout cell line (A549) Human KRTAP23-1 1:3~1:4 Negative Online Inquiry

Background

KRTAP23-1 Gene Knockout Cell Lines are specifically engineered cellular models designed to explore the functional role of the keratin associated protein 23-1 gene in various biological processes. Utilizing state-of-the-art CRISPR-Cas9 technology, these cell lines are created through targeted gene editing, allowing researchers to elucidate the effects of loss of function mutations within the KRTAP23-1 gene.

The primary function of KRTAP23-1 knockout cells is to facilitate the study of keratin intermediate filament dynamics and their implications in cellular structures and functions. By observing the phenotypic changes resulting from the gene knockout, researchers can infer the gene's role in areas such as epidermal development, hair follicle integrity, and skin disease pathogenesis. The mechanism behind this product revolves around its precision; each cell line is validated for specific KRTAP23-1 gene disruption, ensuring reproducibility and reliability in experimental outcomes.

This product holds significant scientific importance as it contributes to understanding keratin-associated disorders, which can have a profound impact on skin health and related conditions. In clinical research, these knockouts can serve as vital models for therapeutic investigations and drug testing, enabling insights into potential treatments for diseases tied to abnormalities in keratin proteins.

KRTAP23-1 Gene Knockout Cell Lines offer distinct advantages over traditional cell lines, including their precise gene targeting, ease of use, and adaptability for high-throughput screening. Unlike other models that may present variable genetic backgrounds, these engineered lines provide a consistent platform, reducing batch-to-batch variability and enhancing the reliability of experimental data.

Researchers and clinicians will find significant value in utilizing these knockout cell lines as they enable hypothesis-driven investigations into the KRTAP23-1 gene, ultimately advancing our understanding of related biological processes and disorders. Our company is dedicated to providing cutting-edge biological products, backed by extensive expertise and a commitment to fostering innovation in life sciences research.

Please note that all services are for research use only. Not intended for any clinical use.

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