KRT23 Knockout Cell Lines

KRT23 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the keratin 23 (KRT23) gene, which plays a crucial role in the structure and function of epithelial tissues. By utilizing CRISPR/Cas9 gene-editing technology, these knockout cell lines effectively eliminate the expression of the KRT23 gene, enabling researchers to investigate the functional impacts of its absence on cellular processes, signaling pathways, and overall cell behavior.

The primary function of KRT23 is to contribute to the structural integrity and mechanical properties of keratinocytes in the epidermis. The knockout cell lines facilitate investigations into how the loss of KRT23 affects cell adhesion, proliferation, and response to stressors, providing insights into skin-related pathologies and diseases such as psoriasis and skin tumors. These cell lines serve not only as valuable tools in basic research but also hold potential applications in drug discovery, toxicology testing, and regenerative medicine.

Compared to traditional cell lines that retain the KRT23 gene, our knockout models allow for a more straightforward investigation of KRT23's functional roles without the confounding effects of its expression. This specificity enhances experimental accuracy and reproducibility, making them indispensable for researchers focused on epithelial biology.

For researchers and clinicians, these KRT23 knockout cell lines represent a powerful resource to deepen understanding of keratin biology and skin disorders, ultimately guiding therapeutic strategies and improving patient outcomes. Furthermore, our company brings years of expertise in genetic engineering and cell line development, ensuring high-quality, reliable products tailored to the complex requirements of modern biological research.