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KMT2E Knockout Cell Lines

Gene: KMT2E

Official Full Name: lysine methyltransferase 2E (inactive)provided by HGNC

Gene Summary: This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07334 KMT2E Knockout cell line (HeLa) Human KMT2E 1:3~1:6 Negative Online Inquiry
KO07335 KMT2E Knockout cell line (HCT 116) Human KMT2E 1:2~1:4 Negative Online Inquiry
KO07336 KMT2E Knockout cell line (HEK293) Human KMT2E 1:3~1:6 Negative Online Inquiry
KO07337 KMT2E Knockout cell line (A549) Human KMT2E 1:3~1:4 Negative Online Inquiry

Background

KMT2E Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the KMT2E gene, a critical player in epigenetic regulation and gene expression. These knockout models are created through CRISPR/Cas9 technology, which allows precise deletion of the KMT2E gene, thereby providing invaluable tools for researchers to investigate the functional role of KMT2E in various biological processes and diseases.

The key function of these knockout cell lines is to enable the observation of cellular phenomena in the absence of KMT2E, allowing scientists to discern the gene’s contributions to chromatin remodeling, histone modification, and transcriptional regulation. By using these unique cell lines, researchers can meticulously explore the impact of KMT2E loss on cellular pathways, signaling mechanisms, and disease phenotypes, leading to a deeper understanding of its implications in oncogenesis, developmental biology, and other critical fields.

The scientific importance of KMT2E Gene Knockout Cell Lines extends beyond academic research; they are pivotal in clinical settings for drug discovery and validation studies. Targeting epigenetic regulators has emerged as a promising therapeutic strategy, and these cell lines provide a robust platform for evaluating novel compounds aimed at modulating the epigenetic landscape.

What sets KMT2E Gene Knockout Cell Lines apart from traditional cell lines is their specificity and precision in gene editing, minimizing off-target effects, which often confound experimental results. Additionally, these cell lines are readily accessible for high-throughput screening, making them an efficient choice for researchers seeking to accelerate their experimental workflows.

Investing in KMT2E Gene Knockout Cell Lines means equipping researchers and clinicians with cutting-edge tools that can enhance understanding, drive innovation, and ultimately pave the way for breakthroughs in health and medicine. Our company is dedicated to providing high-quality, rigorously validated biological products tailored to the needs of the scientific community, ensuring reliability and excellence in every offering.

Please note that all services are for research use only. Not intended for any clinical use.

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