Gene: KLHL36
Official Full Name: kelch like family member 36provided by HGNC
Gene Summary: Enables cullin family protein binding activity. Predicted to be involved in protein ubiquitination. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16648 | KLHL36 Knockout cell line (HeLa) | Human | KLHL36 | 1:3~1:6 | Negative | Online Inquiry |
KO16649 | KLHL36 Knockout cell line (HCT 116) | Human | KLHL36 | 1:2~1:4 | Negative | Online Inquiry |
KO16650 | KLHL36 Knockout cell line (HEK293) | Human | KLHL36 | 1:3~1:6 | Negative | Online Inquiry |
KO16651 | KLHL36 Knockout cell line (A549) | Human | KLHL36 | 1:3~1:4 | Negative | Online Inquiry |
KLHL36 Gene Knockout Cell Lines are an innovative biological research tool developed for the investigation of the KLHL36 gene's role in cellular processes. These specifically engineered cell lines enable the study of gene function through the absence of KLHL36 expression, providing a clear model to analyze its impact on various biological pathways.
The primary function of KLHL36 Gene Knockout Cell Lines is to facilitate functional genomics studies. By utilizing CRISPR-Cas9 technology, these cell lines exhibit a complete knockout of the KLHL36 gene, allowing researchers to observe the resultant phenotypic changes in cellular behavior, signaling pathways, and metabolic processes. The absence of KLHL36 provides insights into its involvement in protein ubiquitination and degradation pathways, mechanisms that are crucial in understanding diseases associated with protein homeostasis and degradation.
The scientific importance of KLHL36 Gene Knockout Cell Lines lies in their versatility for both basic and applied research. In clinical settings, drug discovery and development can greatly benefit from understanding the role of genes like KLHL36 in disease pathology, particularly in cancers or neurodegenerative disorders where protein mismanagement is a concern. Moreover, these knockout models serve as reliable platforms for testing therapeutics aimed at targeting related pathways.
What sets our KLHL36 Gene Knockout Cell Lines apart from alternatives is the precision of the CRISPR technology employed, ensuring a high specificity and efficiency of gene knockout, coupled with robust validation methodologies. This guarantees that researchers can trust the performance and reproducibility of results derived from these cell lines.
For researchers and clinicians, the KLHL36 Gene Knockout Cell Lines are invaluable tools that accelerate discovery and innovation in understanding gene function and disease mechanisms. Our commitment to quality and scientific rigor underlies our extensive expertise in producing reliable and novel biological products, empowering the scientific community to advance their research goals effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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