Gene: KLHL11
Official Full Name: kelch like family member 11provided by HGNC
Gene Summary: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16675 | KLHL11 Knockout cell line (HeLa) | Human | KLHL11 | 1:3~1:6 | Negative | Online Inquiry |
KO16676 | KLHL11 Knockout cell line (HCT 116) | Human | KLHL11 | 1:2~1:4 | Negative | Online Inquiry |
KO16677 | KLHL11 Knockout cell line (HEK293) | Human | KLHL11 | 1:3~1:6 | Negative | Online Inquiry |
KO16678 | KLHL11 Knockout cell line (A549) | Human | KLHL11 | 1:3~1:4 | Negative | Online Inquiry |
KLHL11 Gene Knockout Cell Lines are genetically engineered cell lines designed to specifically ablate the KLHL11 gene, a critical component in various cellular processes including protein degradation and signaling pathways. By utilizing CRISPR/Cas9 gene-editing technology, our knockout cell lines provide a precise model for studying the gene's function and its impact on cellular behavior.
The primary mechanism of the KLHL11 Gene Knockout Cell Lines involves the targeted disruption of the KLHL11 gene, leading to a loss of function that enables researchers to investigate the role of KLHL11 in processes such as cellular differentiation, immune response, and stress response. These knockout models serve as indispensable tools for dissecting the molecular pathways associated with KLHL11, thereby offering insights into its implications in diseases such as cancer and neurodegenerative disorders.
The scientific importance of these cell lines is underscored by their ability to facilitate advanced research into gene function and regulatory networks. In clinical settings, understanding KLHL11's role could pave the way for novel therapeutic strategies targeting its signaling pathways or compensatory mechanisms in disease states.
Compared to alternative gene editing approaches, our KLHL11 Gene Knockout Cell Lines provide superior precision, consistent performance, and reproducibility, which are essential for obtaining reliable experimental data. Researchers will appreciate the ease of use, rapid generation of results, and the ability to conduct high-throughput experiments with these cell lines.
For scientists and clinicians seeking to deepen their understanding of gene functionality and pathogenesis, KLHL11 Gene Knockout Cell Lines represent a vital resource. Their unique capabilities can lead to breakthroughs that are crucial for advancing therapeutic development. Supported by years of expertise in genetic engineering and cell biology, our company is dedicated to providing top-tier biological tools that empower innovation in research and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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