Gene: KLHDC8B
Official Full Name: kelch domain containing 8Bprovided by HGNC
Gene Summary: This gene encodes a protein which forms a distinct beta-propeller protein structure of kelch domains allowing for protein-protein interactions. Mutations in this gene have been associated with Hodgkin lymphoma. [provided by RefSeq, Sep 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37798 | KLHDC8B Knockout cell line (HeLa) | Human | KLHDC8B | 1:3~1:6 | Negative | Online Inquiry |
KO37799 | KLHDC8B Knockout cell line (HCT 116) | Human | KLHDC8B | 1:2~1:4 | Negative | Online Inquiry |
KO37800 | KLHDC8B Knockout cell line (HEK293) | Human | KLHDC8B | 1:3~1:6 | Negative | Online Inquiry |
KO37801 | KLHDC8B Knockout cell line (A549) | Human | KLHDC8B | 1:3~1:4 | Negative | Online Inquiry |
KLHDC8B Gene Knockout Cell Lines consist of genetically engineered mammalian cells in which the KLHDC8B gene has been selectively disrupted. The KLHDC8B gene encodes for a protein associated with various cellular processes, including signal transduction and response to oxidative stress. By using CRISPR/Cas9 technology or other gene editing methods, these cell lines enable researchers to study the functional implications of KLHDC8B deficiency, thereby uncovering its role in physiological and pathological contexts.
The primary function of these knockout cell lines is to facilitate the investigation of gene function and protein interactions, offering a vital tool for elucidating cellular mechanisms underlying diseases. Researchers can employ these models to assess phenotypic alterations, providing insights into how the loss of KLHDC8B affects cellular behavior, proliferation, and apoptosis. This capability is particularly critical in fields such as cancer research, where understanding the molecular basis of tumorigenesis can lead to novel therapeutic strategies.
The scientific importance of KLHDC8B Gene Knockout Cell Lines extends beyond basic research; they can also be instrumental in biopharmaceutical development and personalized medicine, where targeted therapies can be tailored based on genetic profiles. Compared to traditional wild-type cell lines, the knockout counterparts provide a unique advantage in specificity, eliminating confounding factors associated with residual gene expression and allowing for clearer interpretation of experimental outcomes.
Researchers and clinicians will find these cell lines invaluable as they streamline experimental workflows while delivering robust and reliable data. Their development is backed by years of expertise in gene editing techniques and a commitment to quality assurance in biological products, ensuring optimal performance and reproducibility.
[Your Company Name] stands at the forefront of gene editing technology, offering an array of specialized biological products, including KLHDC8B Gene Knockout Cell Lines. This expertise ensures that our customers receive high-quality tools tailored to advance their research and clinical applications effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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